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Saturday, August 13, 2011

Volunteer TMAU test data table

MEBO Research public TMAU database
Currently, the community has no access to trimethylaminuria test data, meaning those with the most interest in finding a cure have no information on testing patterns that may help us to better understand the disorder.

Nigel Manning, the Principal Clinical Scientist of Dept. Clinical Chemistry at Sheffield Children's Hospital and the only current trimethylaminuria phenotype tester in the UK did kindly give MEBO Research a PDF document a while ago that contained much appreciated anonymous information on his testing results of up until 2009.

Sheffield TMAU results up to 2009.
Those to the right are genetic TMAU.
Above the line is trimethylamind (TMA) overload.
According to the reference ranges that Sheffield have set
to help understand TMAU better, MEBO Research have started a voluntary anonymous 'TMAU test result database,' which is available for public viewing. So far only a few testers from the Sheffield lab have kindly added their results. If anyone from anywhere wishes to add their results, they are welcome to do so through this form. There is no need to give any more information than you wish to.

This would also help people understand the different reference ranges and protocols of the labs currently testing. For instance, it is our understanding that the Denver lab expects a person to convert 92% of TMA to trimethylamine N-oxide (TMAO), whereas Sheffield only expects around 82% to be converted from TMA to TMAO. Since TMAU is such a 'neglected' problem, so few labs test for it and there is much more yet to be understood.

The database is held in a Google Docs spreadsheet, and the public version will be a PDF document hosted on the MEBO Research website that will be regularly updated.

(PDF document hosted on the MEBO Research website)

Or you can fill the form below :


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