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DATE: 2 MAY 2017
Currently on : PROGRAM IS TEMPORARILY SUSPENDED

Samples analyzed since June 2012 :
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Metabolomic Profiling Study
NCT02683876

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Blog Archive

Tuesday, October 4, 2011

NEW alveolar breath test for chemicals study

The following is a message from Mike
MEBO Research Managing Director :


MEBO/Mensanna Alveolar Breath Test Study
Okay what’s next from MEBO? Plenty! We have been busy bees launching the TMAU Test Program, and will shortly announce a DNA testing program which fully sequences the coding exons of the FMO3 gene (details to be released soon). However, we are excited to give notice of an Alveolar Breath Test of Chemicals Research Program with Dr. Michael Phillips MD, FACP, FRCP, a world leader in breath analysis. His Breath Collection Apparatus can identify 200 chemicals emitted from the alveolar breath, “system’s analyzers can detect compounds in the breath in concentrations of parts per billion”.

A detection of TMA, along with other sulfides and amines that make good FMO3 substrates, may indicate an FMO3 deficiency and would allow you to correlate the chemical with your odor type.
Menssana Research will conduct a study for Mebo to discover the spectrum of compounds in the breath of systemic body malodor/halitosis sufferers against a normal control group. This is significant as our symptoms can mean changes in the body’s production and use of chemicals called volatile organic compounds (VOCs). Mebo will obtain a Breath Collection Apparatus from Dr. Phillips and obtain alveolar breath samples from sufferers that would like to participate in the study. The research would analyze any volatile organic compound emitted from the upper airway. Menssana Research will desorb the VOCs from the sorbent tubes which will be concentrated in an automated thermal desorber and separated by gas chromatography, each would be identified/quantified by mass spectrometry (GC-MS). The analysis yields approximately 200 compounds in a typical sample of human breath. Chemicals Identified in each alveolar breath sample will be given to the testers, and will be used by Dr. Phillips for the study.

Alveolar Breath Test in Chicago : Would you like to test ?

As a patient advocacy group in the community we wanted to open the study to the community. Since the logistics of obtaining air samples outside the clinical setting is not practical due to the each subject having their own environmental signature, each alveolar breath sample would have to be done directly into the breath machine during a meet up. Two Breath Collection Apparatus systems will be maintained at Mebo’s HQs in Miami and in Chicago. Alveolar breath samples testing will begin in the Chicago area. We will ship Dr. Phillips breath machine to a volunteer that would conduct the breath samples in London or somewhere international where demand exists.

To participate in the study and receive your testing interpretation and reporting, Dr. Phillips has agreed to a low cost to help the community. Each alveolar breath sample will be $345 per subject which covers delivery of samples to the Breath Research Laboratory of Menssana Research.


If you have tested negative for TMAU, this would be an alternative option into researching your body odor/ halitosis condition or PATM condition.
If you have tested negative for TMAU, this would be an alternative option into researching your body odor/ halitosis condition or PATM condition. The biochemist at Menssana says “there is good chance that the breath test will also be able to identify TMA Trimethylaminuria” which would significantly bring value in researching your condition. A detection of TMA, along with other sulfides and amines that make good FMO3 substrates, may indicate an FMO3 deficiency and would allow you to correlate the chemical with your odor type.

This is a great opportunity available from Dr. Phillips and I hope we all take advantage. If you are interested in participating in the program please send an email to mike@meboresearch.org



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2 comments:

Anonymous said...

THIS IS AN INTERESTING ARTICLE WHAT IS THE NAME OF THE SAMPLE COLLECTOR WHEN ELSE WILL THIS EXERCISE BE DONE. I WOULD LIKE TO TAKE PART

Apr 29, 2013, 1:35:00 PM
Maria de la T., Founder and Executive Director, MEBO Research said...

The one-year long data collection period ended (April 2012 - April 2013). We obtained breath samples from Chicago, Miami, New York, and London. Dr. Phillips now has all the results and questionnaires that were filled out by participants, and he and his staff will be analyzing data and documenting their findings. He will eventually publish an article on his findings, at which time it will be shared with the community. As more information is obtained on each participant of this and other studies, the more well-rounded the personal profile will be, thus assisting researchers in their quest for discovering more causes of body odor and halitosis conditions.

Thank you for wanting to participate in research. Please keep an eye out for any future research projects that in time will be announced in this blog.

Apr 29, 2013, 6:31:00 PM
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