Join/Watch the weekly
TMAU UP Podcasts

MEBO Private Facebook Group
to join : contact
maria.delatorre@meboresearch.org

MEBO Map Testing & Meetups


Full details : https://goo.gl/TMw8xu
want listed ? contact map@meboresearch.org

MEBO TMAU urine test

MEBO Research
TMAU Urine Test
United States only
PROGRAM IS PERMANENTLY SUSPENDED AS OF 2 MAY 2017

Click here for
REQUISITION FORM
Incomplete applications
will NOT be processed

SEE UPDATES HERE

1
test
$150 plus
shipping costs
2
tests
$250 plus
shipping costs

TWO PAYMENT PLAN OPTION
Send email to maria.delatorre@meboresearch.org to arrange, AFTER filling out Requisition Form, please.

Test analysis performed in batches of 20 or more

DATE: 2 MAY 2017
Currently on : PROGRAM IS TEMPORARILY SUSPENDED

Samples analyzed since June 2012 :
352
Metabolomic Profiling Study
NCT02683876

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned


Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
EURORDIS and
NORD Member Organization
See RareConnect
BannerFans.com
RESEARCH DETAILS

DONATIONS THRU 31-NOV-2016:
£ 943.03/GBP
$ 568.00/USD

TOTAL at today's ROE
£0.80/GBP = $1.00/USD

£1,398.07 = $1,745.14

MEBO UK PAYPAL FOR TRINZYME

********
MEBO US PAYPAL FOR TRINZYME

Your currency will be automatically converted to USD or GBP by PayPal.

Option: pay with your credit card instead of PayPal account by clicking on either Donate button above.

Popular Posts (last 30 days)

Upcoming get-togethers


Let us know if you want a meetup listed

Subscribe to Blog

Enter your email address:

Delivered by FeedBurner

You will be sent a verification email

Subscribe in a reader

Blog Archive

Tuesday, July 30, 2013

ON PROBIOTICS


COMMENTS TO THIS POST ARE WELCOMED

A discussion to learn from each other

After having tried different probiotics throughout the year, some under my gastroenterologist and dietitian's care, and others recommended to me by healthcare providers of alternative medicine, I would like to share in this blog my thoughts and experiences on the topic. As mentioned previously in this blog, I am not an expert.

there are various classifications of colonies of microbial species in the guts of all human beings around the world
Based on what researchers of gut microflora have told us, there are various classifications of colonies of microbial species in the guts of all human beings around the world. Not all of us have the same gut flora composition, though some of us might have similar ones. Therefore, just based on the different types of colonies that a healthy gut may have from another person’s, it would make sense that blindly taking any brand of probiotics is truly an exercise in trial and error.

If in addition, we have other variances such as lactose intolerance, Crohn’s disease, inflammatory bowel disease (IBD), Irritable Bowel Syndrome, diverticulosis disease, or other disorders, that also play a role on which probiotics will benefit some, while actually causing discomfort in others.

This is why there is so much research taking place now on the study of microbiome, initially with classifying the different groups of microbial colonies in the human gut based and the observing their effect on the body of its host. One can say that we are still in the infancy of this science, which has taken off since microbes can now be identified through their DNA.

I personally am NOT lactose intolerant, and therefore do not need to be concerned about it, so others in this community who are lactose intolerant can discuss using the 'Comment feature' of this post, to describe the effects of the various probiotics on lactose intolerant individuals. I suppose that based of what some sufferers have claimed, that it is important to first determine whether one is lactose intolerant before making a decision of which probiotic to take in order to prevent adverse reactions.

I do suffer from IBS and diverticulosis disease, and I had a very bad case of diverticulitis a few years ago. I was hospitalized and administered antibiotics intravenously for 5 days without being allowed to eat or drink anything – not ever ice chips. After the treatment had been completed, I still had to take additional oral antibiotics at home for a few more weeks. Before discharging me from the hospital, my gastroenterologist told me that my intestines were almost sterile at that point, which is highly dangerous because pathogenic strains could inhabit my gut and thus become life-threatening. I thought he would proceed to say that he would prescribe extremely strong probiotics like prescription strength VSL#3, http://www.vsl3.com/discover.asp. Instead, he said that even though I was going to be taking antibiotics at home, he wanted to start me on the brand, ALIGN, which contains the strain B. infantis 35624. I would not take them together, but instead, would take the probiotics a few hours after the antibiotics. Even though Align is more expensive than some, it is a fraction of the cost of VSL#3. The box claims that it is the #1 most recommended by gastroenterologists. I took it and it helped. However, personally, I find that VSL#3 works the fastest in relieving my IBS symptoms, and I now always take it DURING a course of antibiotics (a few hours after the antibiotics has had a chance to be absorbed from the gut into the bloodstream).

VSL3 is ridiculously expensive, and probably especially so for persons who do not live in the US or UK. I have also tried the brand name Innate, particularly their Flora 20-14 Ultra Strength. This company has stronger clinical strength as well. My mom takes the Innate Colon Care, http://www.innateresponse.com/product-p/41007.htm and it seems to help her.

Some sufferers may find that one brand of probiotics may give them adverse reactions, so they change to a different type and the second one may work well for them. Until researchers make greater discoveries on gut microflora, we are left to explore individually to see what works or doesn't work. I do believe that the general consensus amongst experts is that probiotics are not harmful.

On his webinar, Dr. Robin Lachmann says that it is not necessary to purchase very expensive probiotics because once introduced to the body, the good bacteria colonizes and multiplies on its own. For this reason, I don’t always take probiotics for a very long period of time – it does get expensive. I just stop taking it when I see that my symptoms have subsided, and begin taking them again when the symptoms flare up again.

This is a precise summary of the benefits of probiotics by Ian R. Rowland from a 1992 book by probiotics expert, Roy Fuller.
One of the most important ways in which a probiotic organism may exert a beneficial effect on its host is to modify metabolic processes, particularly those occurring in the gut. Such a beneficial effect could be achieved in theory by a variety of mechanisms:
  1. By suppressing reactions which result in the generation of toxic or carcinogenic metabolites.
  2. By stimulating enzymic reactions involved in detoxification of potentially toxic substances, either ingested or formed endogenously.
  3. By stimulating mammalian enzymes involved in the digestion of complex nutrients, or when such enzymes are absent (due to genetics or disease) providing a bacterial source of these enzymes.
  4. By synthesizing vitamins and other essential nutrients not provided in sufficient quantities in the diet...
Book: Fuller, R. (Ed.). (1992). Probiotics, The scientific basis. London: Chapman & Hall.

Another article from Fuller, R (1991) : from pubmed central



Other posts in this blog on PROBIOTICS:


Summary Blog posts on prebiotics and probiotics


International shopping for probiotics and other supplements








This seems to be an advert for a specific probiotic brand, but is posted rather for the educational purpose, since it's a good intro to probiotics. Please do not take it as a recommendation of the brand. There are many brands in the market.
María María de la Torre Founder and Executive Director A Public Charity maria.delatorre@meboresearch.org www.meboresearch.org www.mebo.com.br/ (em português) MEBO's Blog (English) El Blog de MEBO (español)
get New Posts by EMAIL : Enter your email address :

A EURORDIS and NORD Member Organization

1 comments:

Hope said...

I would like to try VSL3 as I have heard a lot of people make positive comments about it, but this is too expensive for me to get sent to the UK at the moment. I have found it very difficult to find a decent probiotic in the UK. Especially, as far as I am aware, there are no probiotics sold directly from the fridge which makes me wonder how effective they are.

What I have had success with is water kefir. I feel it actually works as when first taking it I have felt die off type reactions such as dizziness. Also slight digestive discomfort when first taking it as my stomach gets used to the beneficial bacteria, this went away after 2 weeks.

What's really good about water kefir is it only cost me an initial £12 for a table spoon of kefir grains. Since then these grains have grown to a massive size and I make at least 6 litres of kefir a week. All I need to add to the grains is 2 spoonfuls of sugar and water so it is a very cheap alternative to shop bought probiotics if people cannot afford them or can't find a brand they trust.

Jul 30, 2013, 3:01:00 PM
Post a Comment