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Blog Archive

Sunday, October 6, 2013

New TMAU paper : Transient Massive Trimethylaminuria Associated with Food Protein-Induced Enterocolitis Syndrome

A new medical paper has been published on a case study of transient Trimethylaminuria in a 8 month old baby. The paper is by clinicians at the Department of Pediatrics, Division of Allergy, Immunology, and Pulmonary Medicine, Washington University School of Medicine, St. Louis.

Only the abstract can be seen for free, but the paper seems to link 'transient TMAU' in this case with 'intestinal permeability' (commonly referred to as 'leaky gut') due to allergies in proteins causing FPIES (see abstract).

In a brief read of the abstract it is not clear what their conclusions are, as they seem to suggest the TMAU is due to 'overload' due to limited FMO3 enzyme reserve capacity, rather than 'leaky gut', but further reading may make it clearer.

It would be interesting to find out if the St Louis hospital tests for TMAU.

Pubmed paper : Transient Massive Trimethylaminuria Associated with Food Protein-Induced Enterocolitis Syndrome

4 comments:

Anonymous said...

Can you contact them and ask them if they've considered it? and Test for it?

Jul 7, 2013, 9:32:00 AM
Anonymous said...

where do we find it so we can read it? did you post the link? the link posted, takes us to a general info page.

Jul 7, 2013, 9:34:00 AM
blogcontributor2 said...

I'm afraid there does not look to be any other free info other than the abstract at the moment. The summary is ahead of print and the paper will probably cost money to view when published.

The paper will be published in the Journal of inherited metabolic diseases http://www.jimd.org/

Jul 7, 2013, 1:32:00 PM
Anonymous said...

If you ask the authors, they might send it to you.

Jul 18, 2013, 2:20:00 AM
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