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Monday, January 23, 2017

How MEBO works in pursuit of answers


Since 2013, Dr. Murat Aydin, DDS, PhD., has shown us how he brakes down halitosis into 5 classifications, Oral, Airway, Gastroensophageal, Bloodborne, and Subjective. Dr. Aydin wrote a paper for MEBO's 2013 Annual Meetup and Conference in Memphis, TN, "How we can understand whether halitosis comes from the mouth or breath?," in which he discusses odorous chemicals that come out of our breath in halitosis, such as,
  1. Volatile sulfur compounds(VSC): hydrogen sulphide, methyl mercaptan, and dimethyl sulfides,
  2. Volatile organic comounds(VOC): alkanes or alkane derivates, with the first three being methyl benzene, tetramethyl butane, and ethanol, short chain acids such as butyric, valeric, isovaleric, lactic, caproic, propionic, succinic, and
  3. Nitrogen containing gases (amines): trimethylamine, ammonia, methenamine, indole, skatole, putrescin, cadaverine.
In addition, one year after he gave us this paper, he published an article in the British Dental Journal, in 2014, "Halitosis: a new definition and classification," in which he elaborates on each of these 5 classifications.
  • Your dentist is the best person to rule out #1, Oral classification.
  • Your Ears, Nose, and throat doctor, Otolaryngologist, can check your sinuses and throat to determine whether this is the cause;
  • your gastroenterologist (GI) can check your esophagus and digestive tract down to your anus, to see if the cause comes from there.
Gastroenterologists are not always trained to be well versed on the newest research projects involving TMA producing bacteria, or other more strictly odor-related conditions. These are relatively new research studies that has not completely been disseminated in the medical community, though MEBO's Raising Awareness Campaign strives for this information to be taught in medical schools and other colleges of the medical field around the world.

This is the reason why MEBO is keeping a close eye on Dr. Hazen's cardivascular disease research to see how his research develops a product that inhibits TMA production by gut bacteria, for example, something that most GIs and cardiologists still are not familiar with, not even to prevent cardiovascular disease. This is how slow news travels in the medical field, unfortunately.

In Dr. Aydin's Bloodborne classification of halitosis TMAU is included. This is why TMAU can cause very strong halitosis.

We hope to discover the cause of the other breath and body odor conditions with the MEBO Metabolomic Profiling Study with the Canadian lab at the University of Alberta. This pilot study is looking for precisely most, if not all, of the odorous compounds Dr. Aydin mentions in his paper, and then some.

MEBO has come a long way forward in our pursuit of answers for body/breath odor conditions since Dr. Aydin came up with his 5 classifications of halitosis four years ago, but we are not at the finish line yet. We're getting there.

María

María de la Torre
Founder and Executive Director

A Public Charity
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1 comments:

Unknown said...

Maria, would it be possible to get the paper as pdf?
awonderland6@googlemail.com
thank you a lot for your post :)

Jan 24, 2017, 9:19:00 AM
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