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Tuesday, April 11, 2017

Metabolic Pathway Simulation: Apocrine Bromhidrosis compared to TMAU

METABOLIC PATHWAY SIMULATIONS
APOCRINE BROMHIDROSIS
COMPARED TO TRIMETHYLAMINURIA

Click for presentation

Danny Kunz has donated a very interesting PowerPoint presentation for the MEBO Conference 2017 consisting of metabolic pathway simulations on Apocrine Bromhidrosis compared to Trimethylaminuria. This presentation also discusses the role of the eccrine glands in bromhidrosis.

We are most grateful to Danny, who is a part of this, "loosely coupled group of patients (and non-patients) with academic degree and without academic degree integrating our separate research capabilities and representing an addressable unit."

This theory is supported by high throughput simulations backed by large enzyme databases, which makes it a very persuasive presentation. In other words, this group has done a computer simulation of bromhidrosis backed up by large enzyme databases, as Danny explains in the presentation. Their theory is that bromhidrosis is an apocrine and eccrine sweat glands metabolic disease.  Danny also says in his presentation that thyroid function with and without elevated hormone, TSH, may plays a role in bromhidrosis, and the group recommends supplementation and diet for this.

Even though the simulations discussed in this PowerPoint presentation do not have the aspect of medical proof yet, it provides a very compelling theory that calls for further research.

TOPIC OF THE PRESENTATION:
1.      Fecal (indole) breath and body odor and it's recommended supplementation and diet, 
2.      Apocrine and eccrine sweat glands metabolic disease in bromhidrosis,
a.      Discussions on isovaleric acid and amino acid leucine in eccrine bromhidrosis,
b.      Recommends a Thyroid functions blood test, with and without elevated Thyroid Stimulating Hormone (TSH), and recommended supplementation and diet.


This very interesting presentation raises question on whether TMAU2 to TMAU1 relation pattern could be transferred to the Bromhidrosis pattern as well.


Click for larger copy

We are most grateful to Danny Kunz and his colleagues for creating this very interesting presentation for our MEBO Annual Conference and Meetup 2017!

María

María de la Torre
Founder and Executive Director

A Public Charity
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