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Wednesday, May 17, 2017

New paper : TMA producing bacteria in human gut

This is a new paper on which gut microbes may produce trimethylamine (TMA) :

Paper :
Uncovering the trimethylamine-producing bacteria of the human gut microbiota.
Silke Rath, Benjamin Heidrich, Dietmar H. Pieper and Marius Vital.
Helmhotz Center for Infection Research, Germany.

It's being posted quickly so people can read it. On 1st glance the specific 'types' of microbes could not be found by us.

It's not known if :
This is new information.
This will be all the gut microbes ever to blame.
If this type of research needs a 'consensus' and papers will show differing results. (i.e. do the experts agree).

So for now, everyone can read the paper at least

Background :
Humans don't 'eat' TMA (it's unpleasant) not produce it in their system. It is sourced from foods and drinks that contain 'TMA precursors', which then microbes break down the precursor and one by-product is TMA.
Known precursors are :
Choline
Carnitine
TMAO (in fish, broken down to TMA)

Currently advice for TMAU is a 'low precurosr' diet, but choline is an important nutrient.

Longterm it would be better for science to come up with a therapy to :
Block of interfere with TMA formation
Alter the flora away from TMA producers
Some other therapy that blocks, interferes or neutralizes TMA in the gut
   

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1 comments:

Anonymous said...

WHAT WE REALLY NEED NOW, IS FOR SOMEONE TO PRODUCE A TMA BLOCKER THAT BLOCKS TMA FROM ENTERING THE GUT AS WELL AS BLOOD STREAM,I'M SURPRISED THAT THIS TYPE OF RESEARCH HAS BEEN GOING ON FOR YEARS, AND NO ONE HAS YET TO FIND A TMA BLOCKER TO BLOCK TMA PRODUCTION, OR A PROBIOTIC THAT WOULD WORK, I JUST DON'T GET IT AT ALL, SO MANY STUDIES BEING DONE WITH LITTLE RESULTS. A TMA BLOCKER WOULD SOLVES ALL THESE PROBLEMS, YET NO ONE HAS YET TO PROVIDE IT.

May 18, 2017, 1:37:00 PM
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