tag:blogger.com,1999:blog-3652036210877702504.post4438290014093177497..comments2024-03-26T08:33:06.926-04:00Comments on The MEBO Blog: Details of the UK Medical Research Council £358K Award for TMAUUnknownnoreply@blogger.comBlogger27125tag:blogger.com,1999:blog-3652036210877702504.post-1024399243293680222016-08-10T14:04:04.069-04:002016-08-10T14:04:04.069-04:00I continue to receive requests for updates on the ...I continue to receive requests for updates on the Trinzyme project in this and other posts and sites. Each phase of the research process takes a long time, and there really isn't much news, except when funding is needed or obtained for the next phase. So, the reply for updates may sound repetitive - like a broken record. This is as frustrating to hear as it is to have to post it over and Maria de la Torrehttps://www.blogger.com/profile/17315221071837223412noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-72033597705200205612015-10-29T08:35:40.088-04:002015-10-29T08:35:40.088-04:00Here is the link where I found this information, u...Here is the link where I found this information, under the section, 'Planned Impact.'<br /><br />"Other beneficiaries include pharmaceutical companies with an interest in both primary TMAU (inherited form and basis of this project) and the treatment of secondary TMAU (acquired form through e.g. gut bacterial overgrowth; bowel surgery; liver dysfunction). Our proposal is focused on Maria de la Torrehttps://www.blogger.com/profile/17315221071837223412noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-46411063547191357742015-10-29T08:33:52.491-04:002015-10-29T08:33:52.491-04:00Hi Cardoso,
I'm sorry you have had to struggle...Hi Cardoso,<br />I'm sorry you have had to struggle with this condition for so many years. Trinzyme is still in the pre-clinical trial phase, which according to the research team, should end within 2 to 5 years. At that time, interested any pharmaceutical companies with interest in both primary and secondary TMAU can develop the therapeutic for clinic and subsequent sales of the product. <brMaria de la Torrehttps://www.blogger.com/profile/17315221071837223412noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-65885548556997129902015-10-29T08:01:18.836-04:002015-10-29T08:01:18.836-04:00My name is Cardoso and I live in Rio de Janeiro, B...My name is Cardoso and I live in Rio de Janeiro, Brazil.<br />Sorry if not expressed myself well, I'm using Google translator.<br />I live in a prison TMAU call, I have 51 years and I still enjoy a bit of life left for me, since I lost my youth and my life is a daily torture.<br />So I ask. There is already some esperimental remedy for TMAU?<br />My email is; ma.foxlight@yahoo.com.br<br /><brEdisonhttps://www.blogger.com/profile/14252891945304715386noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-74374869633415088322015-08-14T16:35:33.834-04:002015-08-14T16:35:33.834-04:00The scientists and MEBO have been trying to get fu...The scientists and MEBO have been trying to get funding for the next few years. Herbal Hill is one of those efforts. However, we are very much aware that we need serious investors, and that's where our primary focus is. <br /><br />This first phase of this research was a very good one, but more phases are needed to complete this.<br />Maria de la Torrehttps://www.blogger.com/profile/17315221071837223412noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-24766175904468799322015-08-14T10:23:54.899-04:002015-08-14T10:23:54.899-04:00I see that the project has been extended to Januar...I see that the project has been extended to January 2016. I am wondering if they will be giving an update soon or in January sometime.<br /><br />I wish I knew if they were doing the human clinical yet.........Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-65337971203873302352015-01-30T10:14:59.359-05:002015-01-30T10:14:59.359-05:00Hi do you know if this project is complete or is i...Hi do you know if this project is complete or is it ongoing?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-43553168940260041262014-09-07T23:06:47.808-04:002014-09-07T23:06:47.808-04:00Thank you for not being offended by my post. The ...Thank you for not being offended by my post. The key is we all need to work together and do our part. Thank you Maria for all you have done and are doing for us. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-32857210909037513272014-09-07T11:39:14.978-04:002014-09-07T11:39:14.978-04:00Also, anonymous, please note that I am also addres...Also, anonymous, please note that I am also addressing many other people who have asked for updates. You are not the only one. I think that posting my reply makes it easier to reach everyone interested in this matter. Thank you for your input.Maria de la Torrehttps://www.blogger.com/profile/17315221071837223412noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-34967163982901864812014-09-07T11:38:01.052-04:002014-09-07T11:38:01.052-04:00This comment has been removed by the author.Maria de la Torrehttps://www.blogger.com/profile/17315221071837223412noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-64346613652131848982014-09-07T11:16:19.077-04:002014-09-07T11:16:19.077-04:00Sorry if my tone doesn't sound right, it was n...Sorry if my tone doesn't sound right, it was not my intention to confuse or offend. I know we were told, as I posted in this blog, that we would receive an update at the end of the year of the research phase. However, we have not received an update as we hoped. <br /><br />It's OK if our researchers take longer than expected, and I'm certain they have valid reasons. Unfortunately, Maria de la Torrehttps://www.blogger.com/profile/17315221071837223412noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-13310296878063744552014-09-06T23:30:02.304-04:002014-09-06T23:30:02.304-04:00By the way who has contacted the researchers to ge...By the way who has contacted the researchers to get an update? Not me. And according to your own post above you mention that we need to ask the researchers for an update. I'm confused by your tone and I am sure I can speak for anyone afflicted with this disorder we do not take for granted this and any other ongoing research. Heck some of us even contributed funds towards it. It was also Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-72855951153983937792014-09-06T16:42:13.383-04:002014-09-06T16:42:13.383-04:00I understand. It's just that they commented o...I understand. It's just that they commented on their website that there would be a progress/update after the first year. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-64719048534108141982014-09-06T14:08:02.658-04:002014-09-06T14:08:02.658-04:00An important thing to realize about researchers is...An important thing to realize about researchers is that they customarily do not discuss their research, and they really don't like doing so, until they have finalized each research phase, at which point they present it in a professional manner in a publication. There is nothing researchers want more than to publish their findings in order to be able to obtain additional grants to go on to Maria de la Torrehttps://www.blogger.com/profile/17315221071837223412noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-70696501921544647642014-09-05T20:04:51.041-04:002014-09-05T20:04:51.041-04:00Maria,
How do we get in touch with Trinzyme to ge...Maria,<br /><br />How do we get in touch with Trinzyme to get an update? Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-68221872929227337062014-08-17T21:38:36.346-04:002014-08-17T21:38:36.346-04:00I hope this is successful.I hope this is successful.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-24441891263641246132014-08-04T18:56:36.469-04:002014-08-04T18:56:36.469-04:00Good question. We need to ask the researchers. H...Good question. We need to ask the researchers. Hopefully, we'll get an update soon.Maria de la Torrehttps://www.blogger.com/profile/17315221071837223412noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-77638585210212950322014-08-04T12:36:47.457-04:002014-08-04T12:36:47.457-04:00Any updates for this month(one year point?Any updates for this month(one year point?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-64144737985739035172014-05-21T12:20:50.982-04:002014-05-21T12:20:50.982-04:00This is such exciting news... I used to be very ac...This is such exciting news... I used to be very active in the tmau community but had to pull away because I felt so helpless reading my same story over and over in others' lives. But this is the first morsel of hope for our community!Anonymoushttps://www.blogger.com/profile/02476112949117561140noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-11619601316225777842014-05-02T10:16:32.146-04:002014-05-02T10:16:32.146-04:00Dr. Shephard tells us that an update will not be a...Dr. Shephard tells us that an update will not be available until after at least one year of the research has been underway. Research is very painstakingly thorough and each detail has to me observed and meticulous documented. This process requires a great deal of time. Hopefully, we will have our first update after August 2014, depending on the outcome of this initial phase of the study.Maria de la Torrehttps://www.blogger.com/profile/17315221071837223412noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-76848850956432336922014-05-01T23:11:53.404-04:002014-05-01T23:11:53.404-04:00Any updates on this research? Are they doing mouse...Any updates on this research? Are they doing mouse studies? Do we know if trinzyme is a probiotic therapy? A treatment for fmo3 deficiency?Anonymoushttps://www.blogger.com/profile/02476112949117561140noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-67953706424078938012013-06-28T11:33:59.709-04:002013-06-28T11:33:59.709-04:00Sorry, I have accidentally removed my reply to the...Sorry, I have accidentally removed my reply to the question, "Is this the same study as Trinzyme. Or are there two studies going on??" <br /><br />Basically, the answer was that Trinzyme is the same study. So the MEBO For Trinzyme Project is the fundraising campaign to support the UK TMAU Therapeutic Research Project for which the PI, Dr. Shephard received £358K research award from MRC.Maria de la Torrehttps://www.blogger.com/profile/17315221071837223412noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-52243355605598758692013-06-27T21:33:18.248-04:002013-06-27T21:33:18.248-04:00I see. Fundraising is crucial. Are we set up to ...I see. Fundraising is crucial. Are we set up to do that internationally?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-52682016107912927792013-06-27T18:44:25.447-04:002013-06-27T18:44:25.447-04:00I believe that the process to get a pharma in the ...I believe that the process to get a pharma in the market accessible to patients has to go through many phases, and ultimately, it has to be approved by the Medicines and Healthcare products Regulator Agency (MHRA), the European Medicines Agency (EMEA) and/or US Food and Drug Administration (FDA), etc. This costs millions of British Pound Sterling, US Dollars... Probably this MRC Award is Maria de la Torrehttps://www.blogger.com/profile/17315221071837223412noreply@blogger.comtag:blogger.com,1999:blog-3652036210877702504.post-71085496764877541722013-06-27T18:23:53.020-04:002013-06-27T18:23:53.020-04:00Thanks Maria.
Is there an estimated window of t...Thanks Maria. <br /><br /> Is there an estimated window of time( ex.1-3 years) for when this would be available to us for treatment??Anonymousnoreply@blogger.com