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MEBO TMAU TESTING CURRENTLY SUSPENDED INDEFINITELY

MEBO - UBIOME study 2018

'PRESS RELEASE'

NCT03582826
ClinicalTrials.gov

MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production
& PATM

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person

NO LONGER RECRUITING

Participation info : LINK English

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Full details : https://goo.gl/TMw8xu
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TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study
NCT02683876

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned


Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
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MEBO Research Clinical Trials

Click here to read details of the MEBO Clinical Trials
NCT03582826 - Ongoing not recruiting
Microbial Basis of Systemic Malodor and PATM Conditions (PATM)
United States 2018 - ongoing

NCT02683876 - Completed
Exploratory Study of Relationships Between Malodor and Urine Metabolomics
Canada and United States 2016 - ongoing

NCT03451994 - Completed
Exploratory Study of Volatile Organic Compounds in Alveolar Breath
United Kingdom and United States 2013 - ongoing

NCT02692495 - Completed
Evaluation of Potential Screening Tools for Metabolic Body Odor and Halitosis
United Kingdom 2009 - 2012

Sunday, November 8, 2009

2nd tester's results in the MeBO-Biolab Gut Dysbiosis in systemic body odor and halitosis study

Currently, MeBO Research is carrying out a study with co-operation from Biolab Medical Unit to determine if people with body odor and/or halitosis have any gut dysbiosis condition as detected by the tests and biomarkers chosen. In our 2nd tester's test results, the biomarkers tested were ethanol for yeast small intestine overgrowth, some alcohols associated with anaerobic gut bacteria overgrowth, fatty acids associated with 'friendly' anaerobic gut bacteria, D-lactate which is associated with lactic acid overgrowth in the small intestine, indicans which is associated with protein bacteria fermentation, and a slight elevation of gut permeability.

The 2nd tester is a lady in her 50s who describes herself as having a sewage/garbage/rotten cabbage/sulfur/damp/dirty odor condition, which she has had for 10-20 years. She believes it is systemic. She has thrush issues, as well as issues with allergies/headaches, cystitis, and constipation. Her TMAU results were negative including the DNA test.

Her results are as follows (to be made into a table later) :

  1. intestinal permeability : Slightly increased permeability to PEG at the midrange level between mwt 374 to 506
  2. indicans : negative
  3. d-lactate : 156 umol/L (normal less than 60)
  4. gut fermentation Profile: raised ethanol fermentation consistent with yeast overgrowth as follows,
  • *ethanol 140 (normal would be less than 22)
  • *some anaerobic bacteria alcohol metabolites were slightly elevated
  • * quite a few 'friendly' bacteria fatty acids were low
More comments will be made on these results later.

The MeBO-Biolab survey is still open to anyone in the UK and Ireland with body odor and/or halitosis, preferably metabolic body odor and/or halitosis, even if you have been diagnosed positive for TMAU. Unfortunately, since MeBO has only just recently begun operating as a non-profit organization, the volunteers would need to pay their test costs (£146). The MeBO questions in the application/survey form are to collate data and look for patterns. Volunteer testers only need to give their name and email address to MeBO in this survey. The other private details will be handled by Biolab directly when you test.



The form to test in MeBO-Biolab Gut Dysbiosis Study is here :
MeBO-Biolab gut dysbiosis in body odor or halitosis study form-REVISED

MeBO is aiming to become a charity, which will cost approximately £1,500.00 to accomplish. Once it achieves this status, it will be in a better position to pursue grants for larger-scale research efforts not only in the UK but abroad as well. MeBO is looking to actively promote research into metabolic body odor and halitosis, especially fecal/gas/garbage body odors (as they are called on the forums). In the meantime, it will continue forward with such studies as this Gut Dysbiosis Study to gather data to identify common patterns amongst sufferers.

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Currently raised:
233.00 GBP = 386.03 USD
06NOV09
Another volunteer has offered to do a larger range of tests soon, which we will post about beforehand. This case study will cost quite a bit more. Biolab has offered a 25% discount for this single case study, and MeBO would like to cover some of this costs, seeing her testing as being for the good of the community. This volunteer wanted to pay for all her test costs, which would be approximately £400 at current estimates (the list of tests isn't confirmed yet), but MeBO would like to pay £125 of this expense. Any contributions towards this £125 target is appreciated. If anyone would like to donate in ways other than through PayPal, please feel free to contact Maria by email, meboresearch@gmail.com.

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