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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

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MEBO Map Testing & Meetups

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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

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Denver TMAU Test Lab survey click here
click to Read more/less

USA survey for anyone who wants to improve Denver TMAU test

begun : Dec22
end : no ending for now

A trainee genetic counselor is working at the Denver TMAU test lab. Probably as part of her training. As a project she wishes feedback on any aspect of the Denver TMAU test and process. You can fill in the survey and/or email her (email address is in survey). It's meant for USA people, but perhaps others can give their view too (as we have so few opportunities).

quote from her rareconnect post

"Hello all! I wanted to make you aware of a research study being conducted to better understand the experience and needs of individuals with trimethylaminuria with a goal of being able to create improved patient and healthcare provider education materials. Any participation is completely voluntary and all responses remain confidential. Feel free to use the contact information within the link with any questions or share the survey with others with TMAU."

see this post for more details

Sunday, October 14, 2012

pilot study : effect of (E, E)-2, 4-Undecadienal in deodorizing trimethylmaine

effect of (E, E)-2, 4-Undecadienal on TMA odor
Pilot Study 2013 (Presumably this copy is ahead of official publication)
Effect of (E, E)-2, 4-Undecadienal on the Offensive Odour of Trimethylamine
Pankaj Garg, Kevin Carpenter, Shanley Chong, John Christodoulou AM

In this study, the object was to see the effect that  (E, E)-2, 4-Undecadienal had on the Offensive Odour of Trimethylamine. The abstract says that  (E, E)-2, 4-Undecadienal is known to have a deodorizing effect on the odor from 'chitlins' (cooked porcine intestines). It was tested in a solution of trimethylamine and volunteers were asked to comment on the effect on the trimethylamine odor.

It is interesting to note that out of 12 people, one person could not detect the odor of trimethylamine at all. The abstract finishes by saying the mechanism for this deodorizing effect is not yet known.

The abstract can be seen here :
A Pilot Study of the Effect of (E, E)-2, 4-Undecadienal on the Offensive Odour of Trimethylamine
related links Identification of (E,E)-2,4-Undecadienal from Coriander (Coriandrum sativum L.) as a Highly Effective Deodorant Compound against the Offensive Odor of Porcine Large Intestine

NORD Member Organization


Anonymous said...

Can we buy the compound ourselves?

Oct 15, 2012, 5:15:00 AM
blogcontributor2 said...

I don't think so yet. I think it can be bought to specialists via specialist chemical companies but not to the public. I'm sure in the future it will likely be packaged as a food grade supplement for human consumption same as chlorophyll or charcoal.

Oct 15, 2012, 12:52:00 PM
Anonymous said...

I think cilantro leaves contain this chemical, and you can find them in the produce department of a grocery store. Search on Google for articles about cilantro erasing the odor of boiling chitlins. Also see the Yahoo message board on TMAU for more discussion.

Oct 15, 2012, 9:25:00 PM
blogcontributor2 said...

Yes it is a chemical found in cilantro/coriander leaves. I suppose the original study was to find what was it in cilantro that most had the deodorizing effect.

Oct 16, 2012, 7:16:00 AM
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