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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

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MEBO Map Testing & Meetups

Full details :
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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Join/Watch the weekly
BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect

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MEBO Research Clinical Trials

Thursday, October 29, 2020

new Monell TMAU page (no longer TMAU test)

Monell Chemical Senses Center now has a TMAU page.

Mainly to redirect people to the Denver TMAU test,
as Monell no longer play a role.

Monell's historic role in USA TMAU testing (via the late Professor George Preti).
Denver is the only source of the TMAU test in the USA (being the 'founder' of TMAU concept).
Dr Paul Fennessey had a connection with the TMAU concept, and enroled his college friend Dr George Preti at Monell as a pathway to the test between sufferers and patients.
Dr Preti also did 1 or 2 papers on TMAU.

Sadly Dr Preti passed in January.
Monell now has no role in TMAU testing.

In memorium of Dr Preti, and also to redirect potential TMAU testers, they have set up a webpage on the Monell site.  

Its 2 roles seem to be :
1. Redirect TMAU testers to the Denver lab, including details
2. A memorial page to Dr Preti's involvement in TMAU.  

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Sunday, October 25, 2020

Daniel latest : TMAU books

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Friday, October 23, 2020

paper : Vit D reduces TMA in mice

new TMA/TMAO paper (China)

Vitamin D Decreases Plasma Trimethylamine-N-oxide Level in Mice by Regulating Gut Microbiota

Quotes :
Vitamin D supplementation significantly reduced plasma TMA and TMAO levels in mice fed a high-choline diet. Furthermore, gut microbiota composition was regulated, and the Firmicutes/Bacteroidetes ratio was reduced by vitamin D. Spearman correlation analysis indicated that Bacteroides and Akkermansia were negatively correlated with plasma TMAO in the HC and HCD3 groups. Our study provides a novel avenue for the prevention and treatment of CVD with vitamin D.


To use covid research as an example of how world research happens.
1. For some reason something becomes important to research.
2. Lots of labs do research on it as individual labs.
3. Each lab asks 'what if this works ? let's try this etc. Other says no.

TMAO is getting similar research treatment by the study labs.
In 2011 Hazen et all said TMAO. (right/wrong?)
Since then lots of TMAO papers about what inhibits TMAO etc.
Lets try this/that.

So it's an interesting paper but perhaps best to wait for a consensus.    

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