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MEBO - UBIOME study 2018

NCT03582826
ClinicalTrials.gov
MEBO Gut Microbiome Study
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production
& PATM

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person

NO LONGER RECRUITING

Participation info : LINK English

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to join : go to
or contact
Ubiome Gut EXPLORER : 10% OFF
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Videos : TMAU stories

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Full details : https://goo.gl/TMw8xu
want listed ? contact map@meboresearch.org
Metabolomic Profiling Study
NCT02683876

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned


Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
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RESEARCH DETAILS

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Blog Archive

Monday, November 12, 2018

Crissan's Mental Health Column: Five effective Stress Management exercises

Five effective Stress Management exercises




NOVEMBER 2018

MEBO Mental Health Monthly Column
MEBO Mental Health Director


STRESS MANAGEMENT
Five effective
Stress Management Exercises

In her October Mental Health Column post, Crissan shares her insightful perspective and professional views on how sufferers can enrich their lives with meaningful relationships. She points out that there are many potential sources of fulfilling relationships that we can tap into. Now in her November Mental Health Column post, she focuses on stress management, the effects it has on the body and mind, and techniques for stress management.


In earlier articles we discussed the effects that stress can have on the body and mind. Stress is a big issue for most malodor and PATM sufferers. The fight-or-flight response can trigger a lot of physical symptoms, it increases tension in the body and stress hormones to soar. When this inborn system is turned on continuously, it can be very damaging and can even cause malodor or PATM symptoms to increase. Relaxation and stress management are thus very important for malodor and PATM sufferers. This is easier said than done of course.

Crissan's indepth article covers the following topics from the perspective of a sufferer and Mental Health Professional:


  • By increasing your awareness of your breathing patterns and shifting to more abdominal breathing, you can balance the oxygen and carbon dioxide blood levels in your body, normalize your heart rate, and reduce the muscle tension and anxiety present with stress-related symptoms or thoughts...
  • Progressive muscle relaxation is an exercise that reduces stress and anxiety in your body by having you slowly tense and then relax each muscle...
  • Mindful- Self-compassion exercise...
  • Autogenic training (AT) has been found to be effective in the treatment of muscle tension and various disorders of the respiratory tract (hyperventilation and bronchial asthma), the gastrointestinal tract (constipation, diarrhea, gastritis, ulcers, and spasms), the circulatory system (racing heart, irregular heartbeat, high blood pressure, cold extremities, and headaches), and the endocrine system (thyroid problems)...
  • Autogenic Formulas for Calming the Mind.


Crissan also recommends a workbook that depicts many more relaxation and stress management techniques. Click on icon to get information on this workbook. Shop around for lowest price.

Our MEBO Mental Health Director, is already planning her December column paper! She gives her heart and soul to lift up our community so that each has the wherewithal to find happiness and peace in life. Thank you, Crissan!


María

María de la Torre
Founder and Executive Director

A Public Charity
maria.delatorre@meboresearch.com
www.meboresearch.org
MEBO's Blog (English)
El Blog de MEBO (español)
MEBO Brasil - Blog (Portuguese)


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Thursday, November 8, 2018

PATM Research Paper 2018

Click on icon to see paper (English translation)
Original in Japanese

PATM Research Paper

Click on icon to see
Power Point Presentation
Yoshika Sekine, PhD, Professor at Tokai University, Japan, President, Society of Indoor Environment, Japan, along with a team of scientists carried out research on PATM Syndrome . We are highly thankful to all of them for giving their precious time to researching and exploring PATM Syndrome.

On April 14, 2018, the Founder and Executive Director of MEBO Research, Maria de la Torre, asked Prof. Sekine to help present his work to raise awareness throughout the globe from the MEBO Annual Conference & Meetup held in Savannah, Georgia this year.Our most sincere thanks to Prof. Yoshika for creating a PowerPoint presentation and providing us with his research paper on the study . We have shared this in many forums through platform of MEBO . The research paper was in Japanese language so MEBO arranged to translate the PATM Syndrome research paper in English language with the help of Director of Community Outreach and Strategy , Mehmet Ali.

Again Sir, thanks you very much for working on this syndrome. Please do not hesitate to contact me if you believe there is anything I can do to support your work.

Research paper is property of Prof. Yoshika and their co-authors and is translated and presented in the MEBO sites with their expressed consent.  We want to raise awareness throughout the globe about PATM syndrome using this effort of Prof and his team of scientists. I hope this information is helpful to other scientists and inspires future research into PATM...



Friday, November 2, 2018

uBiome: World's largest Human Microbiome Dataset

Click on icon
to see full article




uBiome - The Largest
Human Microbiome Dataset



Did you know that uBiome has the largest human microbiome dataset in the world? We're sharing our story of how we built this dataset, what we've learned from it, and what this means for the future of microbiome science.

Initially, uBiome collected 2,500 samples in a crowdfunding campaign. Now, six years later, uBiome has over 250,000 samples from all over the world, with over 1 million projected in 2019.
Click below to read more about what uBiome has learned so far:
As noted in previous posts, MEBO Research is most grateful to uBiome for the research grant they have provided us, which includes providing us with 3 sample collection Explorer Gut kits for over 100 participants around the world and the sequencing of the microbiome of each sample for the Clinical Trial, "Microbial Basis of Systemic Malodor and PATM Conditions (PATM)" registered with ClinicalTrials.gov. To see all posts regarding this research study, click here.

In addition to sequencing the samples of the MEBO participants, they are provided with a comparison of each sample results to those of the 250,000 samples in the uBiome dataset. These results are then given to the Principal Investigator of this study, Dr. Irene Gabashvili, PhD., MEBO Scientific Director, to further analyze these results in relations to odor and PATM conditions. Dr. Gabashvili describes the details of the study:

Human odorprints, mostly owing to the microbiome, have proven their value as biomarkers of health and environmental exposures. In recent years, microbial networks responsible for localized malodors such as halitosis or axillary odor have been mapped by using next generation sequencing approaches. Intestinal microbes responsible for psychologically debilitating systemic malodor (whole-body and extraoral halitosis), however, remain to be identified. Even a relatively straightforward disorder of choline metabolism trimethylaminuria (TMAU) is thought to exhibit complex host-gene microbiome interactions and has not been sufficiently studied.

Proposed controlled pilot study aims to explore the dynamics of microbial communities in remission and flare-up periods. Better knowledge of the important aspects of disease fluctuation should enhance patient care and, combined with our prior data, will help to develop new therapies and treatments.
https://clinicaltrials.gov/ct2/show/NCT03582826

María

María de la Torre
Founder and Executive Director

A Public Charity
maria.delatorre@meboresearch.com
www.meboresearch.org
MEBO's Blog (English)
El Blog de MEBO (español)
MEBO Brasil - Blog (Portuguese)


SUPPORT THE MEBO MISSION: Click Amazon button at right sidebar of this blog when shopping online for the holidays
at no extra cost to you.
MEBO gets small commission from Amazon.

get New Posts by EMAIL : Enter your email address :



A EURORDIS and NORD Member Organization