SC Mitchell, Biological Chemistry, Biomedical Sciences, Faculty of Medicine, Imperial College London
Here's a very interesting article regarding TMAU and halitosis. This refers to the type of bad breath that has nothing to do with infections of the mouth, gums, or teeth.
A small but important percentage of oral malodour cases have an extra-oral aetiology and certain of these fall into the category of ‘blood-borne halitosis’. Odoriferous substances generated within the body and transported to the lungs via the circulatory system may, if sufficiently volatile, leave with the exhaled air and impart a foetid odour to the breath.The aliphatic tertiary amine, trimethylamine, is such a volatile compound that is generated to excess in patients with a metabolic disorder known as trimethylaminuria (fish-odour syndrome). This article highlights this condition and draws attention to its potential role in the causation of recalcitrant oral malodour.
Abstract : http://www.blackwell-synergy.com/doi/abs/10.1111/j.1601-0825.2005.01081.x
Full Article is fee-based
0 comments: