Admin Control Panel

New Post | Settings | Change Layout | Edit HTML | Edit posts | Sign Out


March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

Scroll down and select country

MEBO Map Testing & Meetups

Full details :
want listed ? contact

MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Join/Watch the weekly
BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

Popular Posts (last 30 days)

Upcoming get-togethers

Let us know if you want a meetup listed
Follow MeBOResearch on Twitter

Blog Archive

MEBO Metabolic Malodor Survey (international) for Dr Hazen click here
click to Read more/less

survey for ANYONE who identifies with METABOLIC MALODOR

begun : Oct20
end : no ending for now

Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

This is a GOOGLE FORMS survey

short url for survey :

current participants : 113 (update 18dec20)

Sunday, June 15, 2008

What bloodborne body odor and halitosis means

According to the Merriam-Webster’s Online Dictionary, borne means “to transport or transmit by - used in combination 'soilborne' 'airborne" [1], and the Merriam-Webster’s Medical Dictionary defines blood-borne as “carried or transmitted by the blood”. [2] This could be anything from blood-borne nutrients, blood-borne hormones, a blood-borne disease, etc. Although serious contagious diseases can be blood-borne, most everything that is blood-borne is not a contagious pathogen, and most people don’t have blood-borne contagious pathogens.

Most certainly, metabolic bloodborne body odor/halitosis has nothing to do with contagious/bloodborne pathogens. When we refer to bloodborne body odor, we refer to the abnormal levels of odorous chemicals allowed (mainly) by the liver to enter the main circulation, and the subsequent toxins this imbalance produces that are carried in the main circulating blood and excreted unchanged through the body’s cleansing organs, such as the kidneys, skin, breath (via the lungs), etc. This results in body odor and/or halitosis that stems from the internal system.

The odorous chemicals present in the bloodstream can be the product of a low amount of the metabolic enzyme(s) that otherwise would normally neutralize the odorous chemicals before entering the bloodstream (or in some cases, chemicals produced internally e.g. hormones). Another cause could be simply because the enzyme(s) is completely overloaded (saturated) by the load it has to deal with. For instance if you eat garlic and smell, this is the garlic chemicals overloading an enzyme(s) that is supposed to neutralize the chemicals before they enter the main circulation. And of course, it could also be caused by both.

This concept is mentioned by Dr. Stephen Mitchell, Biological Chemistry, Biomedical Sciences, Faculty of Medicine, Imperial College London, in his article, SC Mitchell (2005) Trimethylaminuria (fish-odour syndrome) and oral malodour, in which he states,

A small but important percentage of oral malodour cases have an extra-oral aetiology and certain of these fall into the category of ‘blood-borne halitosis’. Odoriferous substances generated within the body and transported to the lungs via the circulatory system may, if sufficiently volatile, leave with the exhaled air and impart a foetid odour to the breath. [3]


Post a Comment