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MEBO TMAU TESTING CURRENTLY SUSPENDED INDEFINITELY

MEBO - UBIOME study 2018

'PRESS RELEASE'

NCT03582826
ClinicalTrials.gov

MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production
& PATM

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person

NO LONGER RECRUITING

Participation info : LINK English

MEBO Map Testing & Meetups


Full details : https://goo.gl/TMw8xu
want listed ? contact info@meboresearch.org

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BO Sufferers Podcasts

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Petitions

TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study
NCT02683876

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned


Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
EURORDIS and
NORD Member Organization
See RareConnect

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London TMAU meeting with Prof Liz Shephard
19th Oct 11am - 1pm
St Mary's Hospital
Praed St, Paddington
London W2 1NY
click to read more
more details : karen.james@meboresearch.org

MEBO Research Clinical Trials

Click here to read details of the MEBO Clinical Trials
NCT03582826 - Ongoing not recruiting
Microbial Basis of Systemic Malodor and PATM Conditions (PATM)
United States 2018 - ongoing

NCT02683876 - Completed
Exploratory Study of Relationships Between Malodor and Urine Metabolomics
Canada and United States 2016 - ongoing

NCT03451994 - Completed
Exploratory Study of Volatile Organic Compounds in Alveolar Breath
United Kingdom and United States 2013 - ongoing

NCT02692495 - Completed
Evaluation of Potential Screening Tools for Metabolic Body Odor and Halitosis
United Kingdom 2009 - 2012

Wednesday, July 9, 2008

Co-factors/co-enzymes in enzyme reactions

*unqualified post intended to promote clarification/research :

Many human enzymes require a cofactor for their reaction to take place. In the case of fmo3, B2 (Riboflavin) is needed ?

In theory, if you are deficient in the cofactor, you could in theory end up suffering a version of the problem associated with that enzyme ? For instance possibly B2 deficiency could result in a positive primary trimethylaminuria in a urine test? FMO3 seems to depend on Flavin adenine dinucleotide (FAD), which is derived from B2 (?). However, whatever medical advice was given regards trimethylaminuria results should be regarded as them taking responsibilty for your diagnosis. At the moment it must be deemed unlikely (until research is done) a vitamin/mineral deficiency would be a factor in bloodborne body odor or halitosis issues.

(Unverified) list of vitamins/minerals that are cofactors in human enzymes
http://www.expasy.ch/enzyme/enzyme-bycofactor.html

Reference links :
http://www.chemistryexplained.com/Ce-Co/Coenzyme.html
http://www.encyclopedia.com/doc/1E1-coenzyme.html
http://en.wikipedia.org/wiki/Coenzyme
http://en.wikipedia.org/wiki/Cofactor_(biochemistry)

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