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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect

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MEBO Research Clinical Trials

Click here to read details of the MEBO Clinical Trials
NCT03582826 - Ongoing not recruiting
Microbial Basis of Systemic Malodor and PATM Conditions (PATM)
United States 2018 - ongoing

NCT02683876 - Completed
Exploratory Study of Relationships Between Malodor and Urine Metabolomics
Canada and United States 2016 - ongoing

NCT03451994 - Completed
Exploratory Study of Volatile Organic Compounds in Alveolar Breath
United Kingdom and United States 2013 - ongoing

NCT02692495 - Completed
Evaluation of Potential Screening Tools for Metabolic Body Odor and Halitosis
United Kingdom 2009 - 2012

Wednesday, May 26, 2010

Tester 9 results : MeBO-Biolab gut dysbiosis study

Tester 9
early 30's
Odor problem:
I have been told I smell of poo. there is no range of smells rather very strong (a few feet away range) or very light. Problem for over 10 years. I believe certain foods trigger my smell. milk, cheese and beef are possible triggers.
Gut problems
took regucol and stomach felt terrible had to stop after a few days
Other problems
athletes foot
Trimethylaminurianot tested

Results :
Tester 9
Gut FermentationNo ethanol detected. Apart from acetate, the short chain fatty acids were low, which are produced by normal gut bacteria
body odor gut fermentation
Gut permeabilityIncreased permeability in 2 areas : at 242 and between 300-506
body odor leaky gut
body odor indican & lactate
D-lactate16 (normal is under 60)

Vitamin B2
1.35 : Deficient (normal is less 1.20)
body odor B2

Tester 9 results are back from Biolab, in the systemic body odor gut dysbiosis study. In this case, the person has been suffering from a fecal odor type syndrome for a number of years. In this case, no ethanol was detected in the gut fermentation test, suggesting no yeast overgrowth in the small intestine. However many of the short chain fatty acids were low, which are produced by normal gut bacteria. The lab tester usually suggests with that profile that this could be due to poor fiber intake, diarrhea or a hypoglycemia tendency. Whatever the reason, it seems to imply a deficiency in SCFA's produced by normal gut bacteria. Once again the Vitamin B2 is deficient, making it 3 out of 3 of our testers. Gut permeability was raised over certain levels of molecular size, implying 'leaky gut'. So once again the gut-dysbiosis markers chosen showed up abnormal results although nothing can be concluded at this point.

Anyone wishing to take part in this systemic body odor or halitosis study can fill out the MeBO-Biolab body odor/halitosis gut dysbiosis survey and the process will begin. It would be especially interesting to see how those who were positive for TMAU would get on with these tests. Unfortunately, those overseas from the UK seemingly cannot do the vitamin B2 test, since the sample will likely be spoiled in transit. Testers need to pay for their own tests. The tests are seen only as a starting point for exploratory testing into possible causes of systemic body odor and halitosis.


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