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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info: https://youtu.be/811v7RLXP9M
MEBO Karen
at UK Findacure conf 2020

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MEBO TMAU TESTING DISCONTINUED
(2012-2017)

MEBO Map Testing & Meetups


Full details : https://goo.gl/TMw8xu
want listed ? contact info@meboresearch.org

MEBO - UBIOME study 2018

'PRESS RELEASE'

NCT03582826
ClinicalTrials.gov

MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production
& PATM

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person

NO LONGER RECRUITING

Participation info : LINK English

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to join : go to
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BO Sufferers Podcasts

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Petitions

TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study
NCT02683876

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned


Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
EURORDIS and
NORD Member Organization
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MEBO survey for Dr Hazen click here
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Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

MEBO Research Clinical Trials

Wednesday, May 26, 2010

Tester 9 results : MeBO-Biolab gut dysbiosis study


Tester 9
Male
early 30's
Odor problem:
I have been told I smell of poo. there is no range of smells rather very strong (a few feet away range) or very light. Problem for over 10 years. I believe certain foods trigger my smell. milk, cheese and beef are possible triggers.
Gut problems
took regucol and stomach felt terrible had to stop after a few days
Other problems
athletes foot
Trimethylaminurianot tested


Results :
Tester 9
Gut FermentationNo ethanol detected. Apart from acetate, the short chain fatty acids were low, which are produced by normal gut bacteria
body odor gut fermentation
Gut permeabilityIncreased permeability in 2 areas : at 242 and between 300-506
body odor leaky gut
IndicansNegative
body odor indican & lactate
D-lactate16 (normal is under 60)

Vitamin B2
1.35 : Deficient (normal is less 1.20)
body odor B2

Tester 9 results are back from Biolab, in the systemic body odor gut dysbiosis study. In this case, the person has been suffering from a fecal odor type syndrome for a number of years. In this case, no ethanol was detected in the gut fermentation test, suggesting no yeast overgrowth in the small intestine. However many of the short chain fatty acids were low, which are produced by normal gut bacteria. The lab tester usually suggests with that profile that this could be due to poor fiber intake, diarrhea or a hypoglycemia tendency. Whatever the reason, it seems to imply a deficiency in SCFA's produced by normal gut bacteria. Once again the Vitamin B2 is deficient, making it 3 out of 3 of our testers. Gut permeability was raised over certain levels of molecular size, implying 'leaky gut'. So once again the gut-dysbiosis markers chosen showed up abnormal results although nothing can be concluded at this point.

Anyone wishing to take part in this systemic body odor or halitosis study can fill out the MeBO-Biolab body odor/halitosis gut dysbiosis survey and the process will begin. It would be especially interesting to see how those who were positive for TMAU would get on with these tests. Unfortunately, those overseas from the UK seemingly cannot do the vitamin B2 test, since the sample will likely be spoiled in transit. Testers need to pay for their own tests. The tests are seen only as a starting point for exploratory testing into possible causes of systemic body odor and halitosis.

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