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| click to read halitology abstract |
Prof. Greenman is very likely aware of the work of Drs Wevers and Tangerman regarding dimethylsulfide being an 'extra-oral' cause of halitosis (eg, metabolic). Probably TMAU is mentioned in the overview too. There is a good chance it is a 'cutting edge' overview as far as allopathic medicine is concerned.
However, as halitosis sufferers are probably aware, there's a good chance it misses the 'transient metabolic' cases, where the person probably does not smell at a dental visit. Most of these people are likely to end up classed as 'halitophobic'. There must be a chance inclusion of 'transient metabolic' cases would change the estimates of each category by a considerable amount.
Unfortunately only the abstract is available to read for free.
Halitology : an overview (abstract on pubmed)
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I've got hold of the full PDF. Will summarize when I've read it :).
This being a review, nothing new for those in the know. There is a section on TMAU and a list of other systemic causes.
Mainly it summarizes cause, effect and treatment of halitosis (oral origin) and compares various treatment regimes. The review does mention psycogenic halitosis, but points out that this is a diagnosis which shall only be applied after numerous visits and when all other causes are excluded.
There's also a small section on emerging treatments (for oral halitosis): probiotics, Fusobacterium nucleatum vaccines, myrsinoic acid (inhibits VSC production) and tea catechins (inhibits Porphyromas gingivalis and VSC production).