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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
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Denver TMAU Test Lab survey click here
click to Read more/less

USA survey for anyone who wants to improve Denver TMAU test

begun : Dec22
end : no ending for now

A trainee genetic counselor is working at the Denver TMAU test lab. Probably as part of her training. As a project she wishes feedback on any aspect of the Denver TMAU test and process. You can fill in the survey and/or email her (email address is in survey). It's meant for USA people, but perhaps others can give their view too (as we have so few opportunities).

quote from her rareconnect post

"Hello all! I wanted to make you aware of a research study being conducted to better understand the experience and needs of individuals with trimethylaminuria with a goal of being able to create improved patient and healthcare provider education materials. Any participation is completely voluntary and all responses remain confidential. Feel free to use the contact information within the link with any questions or share the survey with others with TMAU."

see this post for more details

Saturday, January 28, 2012

Halitology : A review paper

click to read halitology abstract
A paper has recently been published which seems to be an overview of halitosis, terming the subject 'halitology'. Professor Greenman has a long interest in halitosis, and is associated with ISBOR. Professor Scully is an esteemed dental surgeon.

Prof. Greenman is very likely aware of the work of Drs Wevers and Tangerman regarding dimethylsulfide being an 'extra-oral' cause of halitosis (eg, metabolic). Probably TMAU is mentioned in the overview too. There is a good chance it is a 'cutting edge' overview as far as allopathic medicine is concerned.

However, as halitosis sufferers are probably aware, there's a good chance it misses the 'transient metabolic' cases, where the person probably does not smell at a dental visit. Most of these people are likely to end up classed as 'halitophobic'. There must be a chance inclusion of 'transient metabolic' cases would change the estimates of each category by a considerable amount.

Unfortunately only the abstract is available to read for free.
Halitology : an overview (abstract on pubmed)


Larc400 said...

I've got hold of the full PDF. Will summarize when I've read it :).

Apr 27, 2012, 5:22:00 PM
Larc400 said...

This being a review, nothing new for those in the know. There is a section on TMAU and a list of other systemic causes.

Mainly it summarizes cause, effect and treatment of halitosis (oral origin) and compares various treatment regimes. The review does mention psycogenic halitosis, but points out that this is a diagnosis which shall only be applied after numerous visits and when all other causes are excluded.

There's also a small section on emerging treatments (for oral halitosis): probiotics, Fusobacterium nucleatum vaccines, myrsinoic acid (inhibits VSC production) and tea catechins (inhibits Porphyromas gingivalis and VSC production).

Apr 28, 2012, 7:15:00 AM
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