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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info: https://youtu.be/811v7RLXP9M
MEBO Karen
at UK Findacure conf 2020

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MEBO TMAU TESTING DISCONTINUED
(2012-2017)

MEBO Map Testing & Meetups


Full details : https://goo.gl/TMw8xu
want listed ? contact info@meboresearch.org

MEBO - UBIOME study 2018

'PRESS RELEASE'

NCT03582826
ClinicalTrials.gov

MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production
& PATM

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person

NO LONGER RECRUITING

Participation info : LINK English

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TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study
NCT02683876

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned


Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
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MEBO survey for Dr Hazen click here
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Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

MEBO Research Clinical Trials

Saturday, January 28, 2012

Halitology : A review paper

click to read halitology abstract
A paper has recently been published which seems to be an overview of halitosis, terming the subject 'halitology'. Professor Greenman has a long interest in halitosis, and is associated with ISBOR. Professor Scully is an esteemed dental surgeon.

Prof. Greenman is very likely aware of the work of Drs Wevers and Tangerman regarding dimethylsulfide being an 'extra-oral' cause of halitosis (eg, metabolic). Probably TMAU is mentioned in the overview too. There is a good chance it is a 'cutting edge' overview as far as allopathic medicine is concerned.

However, as halitosis sufferers are probably aware, there's a good chance it misses the 'transient metabolic' cases, where the person probably does not smell at a dental visit. Most of these people are likely to end up classed as 'halitophobic'. There must be a chance inclusion of 'transient metabolic' cases would change the estimates of each category by a considerable amount.

Unfortunately only the abstract is available to read for free.
Halitology : an overview (abstract on pubmed)

2 comments:

Larc400 said...

I've got hold of the full PDF. Will summarize when I've read it :).

Apr 27, 2012, 5:22:00 PM
Larc400 said...

This being a review, nothing new for those in the know. There is a section on TMAU and a list of other systemic causes.

Mainly it summarizes cause, effect and treatment of halitosis (oral origin) and compares various treatment regimes. The review does mention psycogenic halitosis, but points out that this is a diagnosis which shall only be applied after numerous visits and when all other causes are excluded.

There's also a small section on emerging treatments (for oral halitosis): probiotics, Fusobacterium nucleatum vaccines, myrsinoic acid (inhibits VSC production) and tea catechins (inhibits Porphyromas gingivalis and VSC production).

Apr 28, 2012, 7:15:00 AM
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