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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

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MEBO Map Testing & Meetups

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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

MEBO Private Facebook Group
to join : go to
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Join/Watch the weekly
BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

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MEBO Metabolic Malodor Survey (international) for Dr Hazen click here
click to Read more/less

survey for ANYONE who identifies with METABOLIC MALODOR

begun : Oct20
end : no ending for now

Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

This is a GOOGLE FORMS survey

short url for survey :

current participants : 113 (update 18dec20)

Thursday, June 14, 2012

Age-related odor could be identified in armpit-odor study

Body odors in humans is probably the least understood of the human senses currently. It seems likely that odors will play roles in humans not yet conclusively identified. In animals it is known to have very direct roles; such as in mating. The Monell Chemical Senses Center in Philadelphia is one of the leading research labs interested in human odor and it's role in humans.

Under the leadership of Dr Johan Lundstrom of Monell, a new paper has been published on the ability of volunteers to detect the 'age-group' of armpit odor samples (kept in pads) from 3 groups of different ages. Curiously the older group was said to have the least offensive odor.

Daily Mail article on paper : How you can tell a person's age with just one sniff

Full Research Article : The Smell of Age: Perception and Discrimination of Body Odors of Different Ages

Of course it would seem that abnormal offensive malodors that are not normal metabolic constituents of human sweat would always be an exception to the rule in that they will be expected to repulse anyone at any age. However it seems that FMO3 flaws have survived given that they seemingly do no good and cause offence to those who can detect trimethylamine or perhaps other FMO3 unmetabolized malodors.

There has been previous coverage of how a mutation to do with wet or dry earwax may also perhaps be linked with hypohydrosis in armpit sweat in a Far East population that then came to be the main type that Far East Asians are now expected to carry. One hypothesis is that this mutation becoming the dominant type there may be because the lack of ability to have sweaty armpit odor would make the person a more attractive mate.

2009 paper : A strong association of axillary osmidrosis with the wet earwax type determined by genotyping of the ABCC11 gene

Other links of interest
Preti and Leyden paper 2010 : Genetic Influences on Human Body Odor: From Genes to the Axillae


Anonymous said...

I control my body odour by keeping my body fat as low as possible. It has worked for me for the last few months.

Jun 15, 2012, 10:59:00 AM
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