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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
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Denver TMAU Test Lab survey click here
click to Read more/less

USA survey for anyone who wants to improve Denver TMAU test

begun : Dec22
end : no ending for now

A trainee genetic counselor is working at the Denver TMAU test lab. Probably as part of her training. As a project she wishes feedback on any aspect of the Denver TMAU test and process. You can fill in the survey and/or email her (email address is in survey). It's meant for USA people, but perhaps others can give their view too (as we have so few opportunities).

quote from her rareconnect post

"Hello all! I wanted to make you aware of a research study being conducted to better understand the experience and needs of individuals with trimethylaminuria with a goal of being able to create improved patient and healthcare provider education materials. Any participation is completely voluntary and all responses remain confidential. Feel free to use the contact information within the link with any questions or share the survey with others with TMAU."

see this post for more details

Thursday, June 14, 2012

Age-related odor could be identified in armpit-odor study

Body odors in humans is probably the least understood of the human senses currently. It seems likely that odors will play roles in humans not yet conclusively identified. In animals it is known to have very direct roles; such as in mating. The Monell Chemical Senses Center in Philadelphia is one of the leading research labs interested in human odor and it's role in humans.

Under the leadership of Dr Johan Lundstrom of Monell, a new paper has been published on the ability of volunteers to detect the 'age-group' of armpit odor samples (kept in pads) from 3 groups of different ages. Curiously the older group was said to have the least offensive odor.

Daily Mail article on paper : How you can tell a person's age with just one sniff

Full Research Article : The Smell of Age: Perception and Discrimination of Body Odors of Different Ages

Of course it would seem that abnormal offensive malodors that are not normal metabolic constituents of human sweat would always be an exception to the rule in that they will be expected to repulse anyone at any age. However it seems that FMO3 flaws have survived given that they seemingly do no good and cause offence to those who can detect trimethylamine or perhaps other FMO3 unmetabolized malodors.

There has been previous coverage of how a mutation to do with wet or dry earwax may also perhaps be linked with hypohydrosis in armpit sweat in a Far East population that then came to be the main type that Far East Asians are now expected to carry. One hypothesis is that this mutation becoming the dominant type there may be because the lack of ability to have sweaty armpit odor would make the person a more attractive mate.

2009 paper : A strong association of axillary osmidrosis with the wet earwax type determined by genotyping of the ABCC11 gene

Other links of interest
Preti and Leyden paper 2010 : Genetic Influences on Human Body Odor: From Genes to the Axillae


Anonymous said...

I control my body odour by keeping my body fat as low as possible. It has worked for me for the last few months.

Jun 15, 2012, 10:59:00 AM
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