Admin Control Panel

New Post | Settings | Change Layout | Edit HTML | Edit posts | Sign Out


March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

Scroll down and select country

MEBO Map Testing & Meetups

Full details :
want listed ? contact

MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Join/Watch the weekly
BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

Popular Posts (last 30 days)

Upcoming get-togethers

Let us know if you want a meetup listed
Follow MeBOResearch on Twitter

Blog Archive

Denver TMAU Test Lab survey click here
click to Read more/less

USA survey for anyone who wants to improve Denver TMAU test

begun : Dec22
end : no ending for now

A trainee genetic counselor is working at the Denver TMAU test lab. Probably as part of her training. As a project she wishes feedback on any aspect of the Denver TMAU test and process. You can fill in the survey and/or email her (email address is in survey). It's meant for USA people, but perhaps others can give their view too (as we have so few opportunities).

quote from her rareconnect post

"Hello all! I wanted to make you aware of a research study being conducted to better understand the experience and needs of individuals with trimethylaminuria with a goal of being able to create improved patient and healthcare provider education materials. Any participation is completely voluntary and all responses remain confidential. Feel free to use the contact information within the link with any questions or share the survey with others with TMAU."

see this post for more details

Friday, June 1, 2012

Hormonal influence on olfactory acuity as well as body and breath odor

An article written by the Food Neurochemistry Lab at the University of Panama, The amelioration of olfactory acuity upon sexual maturation might affect food preferences, raises an interesting point about olfactory acuity in women improving as one matures sexually (15-44 year-old women). Even more interesting, it discusses how the olfactory acuity seems to fluctuate throughout the menstrual cycle, “During ovulation, mean olfactory threshold is 30 times lower than during bleeding.”

During ovulation, mean olfactory threshold is 30 times lower than during bleeding. Interestingly, menstruated women undergo maleodorant trimethylaminuria. We argued that olfactory amelioration during ovulation might concur to a mating strategy, whereas olfactory impairment during bleeding might protect women against self-refusal.
The explanation given seems to be more focused on testosterone levels, as opposed to estrogen levels in women, as the testosterone derivative “might be responsible for the synchronization of these menstrual events.”

One of MEBO’s Scientific Advisors and pioneer in the science of TMAU, Dr. John Cashman of HBRI and Professor Yamazaki, et al., have published a paper, Transient trimethylaminuria related to menstruation (2007), in which they conclude,

…these results indicate that abnormal FMO3 capacity is caused by menstruation particularly in the presence, in homozygous form, of mild genetic variants such as [Glu158Lys; Glu308Gly] that cause a reduced FMO3 function.

there seems to be a parallel pattern between increased olfactory acuity and transient TMAU in sufferersAs a community of body odor and halitosis sufferers, we consequently raise the following questions as to whether a similar effect of hormonal changes hold true in relation with body and breath odor conditions. Based on these papers, there seems to be a parallel pattern between levels of olfactory acuity and transient TMAU in sufferers.

The figures used in this article present a

Hypothetical view of the multiple physiological processes concurring to modulate olfaction and liver FMO3 enzyme activity i women during menses. (CYP19A1 = Aromatase enzyme; Estradiol = 17β-Estradiol; TMA = Trimethylamine; TMAO = Trimethylamine oxide; FMO3 = Flavin mono-oxygenase 3; DA interneurons = Dopaminergic neurons; hPR = Progesterone receptor).

See other posts in this blog under the label "hormones" (and scroll down to see them all) related to the effects of hormonal changes body/breath odor.


María de la Torre
Founder and Executive Director

A Public Charity
MEBO's Blog (English)
El Blog de MEBO (español)
MEBO Brasil - Blog (Portuguese)

SUPPORT THE MEBO MISSION: Click Amazon button at right sidebar of this blog when shopping online for the holidays
at no extra cost to you.
MEBO gets small commission from Amazon.

Please use your credit card to make your donation to MEBO.

Subscribe for latest posts : Enter your email address:

Delivered by FeedBurner

A EURORDIS and NORD Member Organization


Post a Comment