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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

Scroll down and select country

MEBO Map Testing & Meetups

Full details :
want listed ? contact

MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Join/Watch the weekly
BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

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MEBO Metabolic Malodor Survey (international) for Dr Hazen click here
click to Read more/less

survey for ANYONE who identifies with METABOLIC MALODOR

begun : Oct20
end : no ending for now

Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

This is a GOOGLE FORMS survey

short url for survey :

current participants : 113 (update 18dec20)

Wednesday, June 6, 2012

Update: Menssana Alveolar Breath Test Study

The Menssana Alveolar Breath Test exploratory study is moving along quite well. As a reminder any donations to the program may be tax deductible (please discuss this with your tax accountant). 1. Any donations to the program may be tax deductible
2. We all know there is no alternative testing to TMAU
3. Irene will review results of computational analysis and Alveolar Breath Test, and give an assessment/ interpretation of your health profile with Aurametrix.

The results we have received back so far from the initial testers are very uplifting. If you have not seen the sample test results from the earlier post by MEBO, Menssana is able to identify many compounds by name, and provide their alternative names. These compounds are matched to the NIST (National Institute of Standard and Technology) Chemistry Webbook. I know some testers have asked the question, now that I have a list of chemicals from my breath what do I do?

Obviously, this is difficult for MEBO as we want to help sufferers find answer immediately, and understanding this is an exploratory study, the conclusion of the results will not be rendered until the one-year study is completed in April 2013. And we hope sufferers understand this, which most do, since we all know there is no alternative testing to TMAU. Researching each compound using PubMed or MEDLINE will definitely help you in your efforts.

I spoke with Dr. Irene Gabashvili, one of MEBO’s Scientific Directors, and Irene has offered her custom program, Aurametrix, to Breath Testers of the Menssana Alveolar Breath Exploratory Study, who will be able to enter their “Aura” for 5 days, and Irene will review results of computational analysis and breath testing, and give an assessment/interpretation of your health profile. I want to thank Irene for her generous offer to do this. I believe this will help sufferers tremendously. To those that are not familiar with Aurametrix, it is a dynamic program that associates symptoms with triggers associated with body odor, or any other ailment, by keeping a log of your food intake, environment, and your “Aura” - that is how you are feeling relative to the day. It is a very simple tool that allows you to connect the dots (scroll down to see all posts on Aurmetrix) of anything you consume to how you feel. I high recommend the program. I do want to reiterate that Aurametrix is unrelated to the breath test or any other test offered by MEBO.

So far we have not had enough data to make reasonable or detailed assessments, but I would like to highlight a few tester profiles. This is not medical advice or an interpretation of any kind. I am not a medical professional.
  • Testers that complained of Halitosis found a majority of their top 20 VOCs emitted from the breath to be sulfurous compounds, all varied by their compound names.
  • The array of sulfurous compounds demonstrates that the breath test itself is capturing compounds from the oral cavity and the alveolar breath.
  • The commonality between testers was an elevated alveolar gradient of the compound Heptane, 2,4,6-trimethyl or tridecane and Octane,2,3,6-trimethyl compared to the abundance of air.
  • According to a blog post made by Aurametrix, Derivatives of cyclic hydrocarbons - such as Cyclopropane, Limonene, Benzene, Longifolene, and simpler hydrocarbons - Tridecane, Tetradecane, Pentadecane, along with fatty alcohols (octanol) were compounds that range from lemony to gasoline fumes, rubber and stinky bugs.
Testers confirmed fasting prior to the test, which indicates that higher level of sulfur compounds existed in the oral cavity or tongue even before eating. Which one can only assume that these levels may stay constant or increase in levels depending on the type of food intake. One tester tested previously with organoleptic measurements and gas chromatography, and showed measurements consistent with oral halitosis. It is still unclear for these testers the cause, whether the origination is from intra-oral or extra-oral halitosis or both. A report labeled “An Extra-oral halitosis: An Overview” by A Tangerman and E G Winkel indicates

Most reports now agree that the most frequent sources of halitosis exist within the oral cavity and include bacterial reservoirs such as the dorsum of the tongue, saliva and periodontal pockets, where anaerobic bacteria degrade sulfur-containing amino acids to produce the foul smelling volatile sulfur compounds (VSCs), especially hydrogen sulfide (H(2)S) and methyl mercaptan (CH(3)SH).
The mouth accumulates bacteria and foods that contain amino acids, which convert into sulfurous compounds, and foods that contain sugar can increase the amount of harmful bacteria in the mouth causing malodor.

We are working hard to keep the study moving so please remember that this is a multi-site study, and the equipment will be moved onto the next site. We have already received some requests in the Chicago area and unfortunately, these testers will have to wait and see if there is enough demand in Chicago for a later testing date. This might never come to fruition due to the study only being one year in length. We have shipped the Breath Test equipment from Chicago, IL to Miami, FL to prepare for the Miami meet up in a couple of weeks. If you have not already done so, please fill out the requisition form to show your interest. It is important to state your preferred testing location. If you have already filled out the requisition form, you should have already received an invoice from Maria. If you have not received it, please let her know.

As participants of this exploratory study, you can take pride in being a pioneer in our community paving the way towards new discoveries that could change the lives of sufferers around the world and their offsprings.

Managing Director
MEBO Research

MEBO Research


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