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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
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MEBO Research Clinical Trials

Wednesday, February 6, 2013

Graph of TMAU results from Sheffield 1997-2012

Sheffield TMAU results : 1997 - 2012
Graph of TMAU urine test results tested at Sheffield Children's Hospital 1997-2012

Kindly given to MEBO Research by the tester ; Nigel Manning : Principal Clinical Scientist, Dept of Clinical Chemistry, Sheffield Children's Hospital, Sheffield.

Nigel Manning has kindly given MEBO Research a graph of all the TMAU biochemical test results done by his lab at Sheffield Children's Hospital since his lab started testing in 1997 up until the end of the 2012. This is an updated graph of one given to MEBO Research in a previous year.

Sheffield Children's Hospital TMAU urine test reference range :
The lab tests the trimethylamine and trimethylamine oxide levels in urine samples. The reference ranges used by the lab are (for a normal person):
That the TMA level should be lower than 11 umols/mmol creatinine
That the TMA/TMAO ratio should be lower than 0.21 (this as a % works out at >79% TMAO)

So from the graph it can be seen that those in the small square in the bottom left are 'normal'. Those above the horizontal red line have TMAU2 (too much trimethylamine), and those to the right of the vertical red line have genetic TMAU (TMA/TMAO ratio too high). In total, 1731 samples have been tested in the graph.


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