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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect

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Blog Archive

MEBO Research Clinical Trials

Click here to read details of the MEBO Clinical Trials
NCT03582826 - Ongoing not recruiting
Microbial Basis of Systemic Malodor and PATM Conditions (PATM)
United States 2018 - ongoing

NCT02683876 - Completed
Exploratory Study of Relationships Between Malodor and Urine Metabolomics
Canada and United States 2016 - ongoing

NCT03451994 - Completed
Exploratory Study of Volatile Organic Compounds in Alveolar Breath
United Kingdom and United States 2013 - ongoing

NCT02692495 - Completed
Evaluation of Potential Screening Tools for Metabolic Body Odor and Halitosis
United Kingdom 2009 - 2012

Wednesday, February 5, 2014

MEBO TMAU Test Program Results: BATCH #8

Click on icon to see chart

The MEBO Research TMAU urine test program was launched in June 2012, and 172 tests have been analyzed. The results of Batch #8 TMAU urine tests were received on January 31, 2014, and all the individuals tested received their respective results within two days after MEBO received all the results in a spreadsheet from the lab.

Of the 15 samples in Batch #8, three were indicative of Primary TMAU (TMAU1) and four of Secondary TMAU (TMAU2), as compared to Batch #7, which had only one TMAU1 and five TMAU2. The results of each batch seem to be different from each other. The more tests are performed, the better we get a clearer picture of averages.

As noted in the comparison chart, which presents the highest to lowest figures per category, TMA, TMAO, TMA/TMAO Ratio, the following are the averages of all the results of 172 tests:

Primary TMAU (TMAU1) Positives: 8.14% (14 of 172)*

Secondary TMAU (TMAU2) Positives: 28.49% (49 of 172)

TOTAL TMAU POSITIVE: 36.62% (63 of 172)

TOTAL NEGATIVE FOR TMAU: 63.37% (109 of 172)

*Please note that 4 of the 14 TMAU1 positive results are repeats by the same people who wanted to see if TMA decreased with the TMAU odor-managment protocol. Even though their TMA levels decreased, the TMA/TMAO Ratio remained in the Above Normal Range, and thus indicative of Primary TMAU. Therefore, Primary TMAU, consisting mostly of genetic causes, is still considered a rare disorder with 5% or less (5 in 10,000 people).

The only way to confirm the genetic form of TMAU originally positive urine test is with a DNA test. See article written by Drs. Elizabeth Shephard and Ian Phillips, "Differential Diagnosis" in NCBI, NIH pages.

Although it took longer to get the test results for Batch#8 due to extreme arctic weather conditions in the Eastern and Midwestern US this winter, thankfully, no samples were damaged, thanks to the care and patience of everyone involved.

For more information, please see all the posts in this blog regarding, the TMAU Test Results.

How to test for TMAU with MEBO :

Click here

TMAU Test Requisition Form

No additional cost throughout the test process will be incurred
after initial payment of test & round trip shipping


María de la Torre
Founder and Executive Director

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