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uBiome - The Largest
Human Microbiome Dataset
Did you know that uBiome has the largest human microbiome dataset in the world? We're sharing our story of how we built this dataset, what we've learned from it, and what this means for the future of microbiome science.
Initially, uBiome collected 2,500 samples in a crowdfunding campaign. Now, six years later, uBiome has over 250,000 samples from all over the world, with over 1 million projected in 2019.
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In addition to sequencing the samples of the MEBO participants, they are provided with a comparison of each sample results to those of the 250,000 samples in the uBiome dataset. These results are then given to the Principal Investigator of this study, Dr. Irene Gabashvili, PhD., MEBO Scientific Director, to further analyze these results in relations to odor and PATM conditions. Dr. Gabashvili describes the details of the study:
Human odorprints, mostly owing to the microbiome, have proven their value as biomarkers of health and environmental exposures. In recent years, microbial networks responsible for localized malodors such as halitosis or axillary odor have been mapped by using next generation sequencing approaches. Intestinal microbes responsible for psychologically debilitating systemic malodor (whole-body and extraoral halitosis), however, remain to be identified. Even a relatively straightforward disorder of choline metabolism trimethylaminuria (TMAU) is thought to exhibit complex host-gene microbiome interactions and has not been sufficiently studied.
Proposed controlled pilot study aims to explore the dynamics of microbial communities in remission and flare-up periods. Better knowledge of the important aspects of disease fluctuation should enhance patient care and, combined with our prior data, will help to develop new therapies and treatments.
https://clinicaltrials.gov/ct2/show/NCT03582826
María
María de la TorreFounder and Executive Director
A Public Charity
maria.delatorre@meboresearch.com
www.meboresearch.org
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2 comments:
I THINK THAT ITS SO SAD THAT THIS IS ALL THEY HAVE COME UP WITH SINCE 1970, WHICH IS WHEN ONE OF THE FIRST CASES OF TMAU HAS BEEN BROUGHT UP, I MEAN, THESE SCIENTIEST MUST KNOW SOMETHING BY NOW ABOUT HOW TO STOP TMAU ODORS, COME ON PEOPLE, A PERSON WITH TMAU IS GOING TO BE THE ONE TO FIGURE THIS OUT BEFORE THE SCIENTIST DO,I HEAR OF PEOPLE WANTING TO KILL THEMSELVES OVER THIS CONDITION BECAUSE OF THE RIDICULE THATS PLACED UPON THEM, SO MUCH MORE NEEDS TO BE DONE, PEOPLE ARE CONTEMPLATING SUICIDE FOR GOD SAKE. PROCTOR AND GAMBLE HAS A PILL WAITING FOR 2020 TO PUT ON THE MARKET, BUT WHY WAIT UNTIL THEN, PEOPLE ARE DYING. I JUST DON'T GET IT AT ALL.
GRACIAS MARIA POR SU FUNDACION