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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

MEBO Karen
at UK Findacure conf 2020

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MEBO TMAU TESTING DISCONTINUED
(2012-2017)

MEBO Map Testing & Meetups


Full details : https://goo.gl/TMw8xu
want listed ? contact info@meboresearch.org

MEBO - UBIOME study 2018

'PRESS RELEASE'

NCT03582826
ClinicalTrials.gov

MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production
& PATM

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person

NO LONGER RECRUITING

Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Join/Watch the weekly
BO Sufferers Podcasts

MEBO TMAU Videos

Petitions

TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study
NCT02683876

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned


Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
EURORDIS and
NORD Member Organization
See RareConnect

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MEBO Research Clinical Trials

Click here to read details of the MEBO Clinical Trials
NCT03582826 - Ongoing not recruiting
Microbial Basis of Systemic Malodor and PATM Conditions (PATM)
United States 2018 - ongoing

NCT02683876 - Completed
Exploratory Study of Relationships Between Malodor and Urine Metabolomics
Canada and United States 2016 - ongoing

NCT03451994 - Completed
Exploratory Study of Volatile Organic Compounds in Alveolar Breath
United Kingdom and United States 2013 - ongoing

NCT02692495 - Completed
Evaluation of Potential Screening Tools for Metabolic Body Odor and Halitosis
United Kingdom 2009 - 2012

Sunday, December 22, 2019

$12 million NIH grant to Hazen lab for TMAO/microbiome research

$12 million grant from NIH.
Press release says first big grant from NIH into the gut microbiome.
to : Dr Hazen et al at Cleveland Clinic.
research : How TMAO and microbiome affects Cardiovascular Disease.
why ? : Hazen et al put forward a new hypothesis in 2011, that TMAO damages the cardiovascular system.

Dr Stanley Hazen et al at Cleveland Clinic got a new big grant from the NIH to continue their research into TMAO causing CVD
Cleveland Clinic press release Nov 2019

What has this to do with Metabolic Body Odor  ?
It will lead to more research into TMA metabolism in humans, and probably therapies to inhibit TMA generation in the gut. 
This grant is wider in context than TMAO only. It will look at the microbiome.

The program will consist of three specialized projects and four supporting cores. The projects will:
- explore how newly identified gut microbial pathways affect thrombosis and atherosclerosis
- investigate how microbial metabolites act like hormones to drive disease in a high-fat environment
- and identify specific microbial genes and metabolites that are responsible for enhancing cardiovascular disease.
The three projects will be led by Drs. Hazen and Brown, both of Cleveland Clinic’s Lerner Research Institute, and Dr. Michael Fischbach, of Stanford University. The four supporting cores will be led by Drs. Hazen, Brown, Wang and Hajjar, all from the Lerner Research Institute.

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A EURORDIS and NORD Member Organization

1 comments:

Anonymous said...

Any news on the Procter & Gamble research?

Dec 26, 2019, 9:10:00 PM
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