Press release says first big grant from NIH into the gut microbiome.
to : Dr Hazen et al at Cleveland Clinic.
research : How TMAO and microbiome affects Cardiovascular Disease.
why ? : Hazen et al put forward a new hypothesis in 2011, that TMAO damages the cardiovascular system.
Dr Stanley Hazen et al at Cleveland Clinic got a new big grant from the NIH to continue their research into TMAO causing CVD
Cleveland Clinic press release Nov 2019
What has this to do with Metabolic Body Odor ?
It will lead to more research into TMA metabolism in humans, and probably therapies to inhibit TMA generation in the gut.
This grant is wider in context than TMAO only. It will look at the microbiome.
The program will consist of three specialized projects and four supporting cores. The projects will:
- explore how newly identified gut microbial pathways affect thrombosis and atherosclerosis
- investigate how microbial metabolites act like hormones to drive disease in a high-fat environment
- and identify specific microbial genes and metabolites that are responsible for enhancing cardiovascular disease.
The three projects will be led by Drs. Hazen and Brown, both of Cleveland Clinic’s Lerner Research Institute, and Dr. Michael Fischbach, of Stanford University. The four supporting cores will be led by Drs. Hazen, Brown, Wang and Hajjar, all from the Lerner Research Institute.
1 comments:
Any news on the Procter & Gamble research?