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MEBO - UBIOME study 2018

MEBO Gut Microbiome Study
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person

Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Ubiome Gut EXPLORER : 10% OFF
Join/Watch the weekly
TMAU UP Podcasts

Videos : TMAU stories

MEBO Map Testing & Meetups

Full details :
want listed ? contact
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect

£ 943.03/GBP
$ 568.00/USD

TOTAL at today's ROE
£0.80/GBP = $1.00/USD

£1,398.07 = $1,745.14



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Friday, April 8, 2011

Table of FMO3 variants provided by Dr John Cashman

Table of FMO3 variants provided by Dr John Cashman 

Dr John Cashman kindly provided some of his research papers for us to view at the Washington meetup. We have chosen to look at the table of FMO3 variants in one of these papers.

As seen in Prof Elizabeth Shephard's slideshow, the FMO3 protein consists of 532 amino acids. Whilst building these amino acids, in theory it means there could be 532 points where mutations could occur that would affect the construction of the final FMO3 protein.

In this table, Dr Cashman has listed some of the common amino acid numbers where mutations occur. Some are severe mutations, other have less or no effect, although some can reduce activity if in combination with another (such as 158 - 258)

Notice that one change to amino acid 158 is about 40% common in ethnic groups.

2.5% have a combo of 158 - 308 which is said to be present in 2.5% of the population. However, this is only regarded as likely to cause a mild deficiency in FMO3 function if both the mutations are on the same chromosome (i.e. from the same parent) .

The paper also lists some drugs that commonly use FMO3 function and the affect a deficiency may have on them.


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