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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
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$ 568.00/USD

TOTAL at today's ROE
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Tuesday, November 15, 2011

Nasal Halitosis Treatment

As mentioned frequently in the forums, many sufferers of chronic halitosis claim that their odor not only comes from their mouth, but also from their nasal breath. The odor can be detected by others from the air only coming out of the sufferer's nose when breathing with his or her mouths closed. Some sufferers have already gone to see an Ear, Nose, and Throat specialist (ENT, or Otolaryngologist), and were told that they have no infection, and possibly some have been told that they suffer from allergies with excess nasal secretions.

The odor can be detected by others from the air only coming out of the sufferer's nose when breathing with his or her mouths closed.
In the same way that trimethylamine (TMA) gives off body odor/halitosis "that results from excess excretion of trimethylamine in the urine, breath, sweat, and reproductive fluids," as noted in GeneReviews - NCBI Bookshelf of the U.S. National Library of Medicine, NIH, the same can be said of any other volatile organic compound (VOC), possibly resulting from another metabolic deficiency, excreted by the body in its bodily fluids and mucous membranes. Our bodies try to excrete VOCs through our cleansing organs, including the oral and nasal mucous membrane as well as in saliva.

Sufferers of nasal halitosis are encouraged to discuss with their doctor the possible treatment option with a NasoNeb Nasal Nebulizer. Your doctor would be the best judge which medication to use with your NasoNeb, and possibly simply a deep cleansing with saline solution may help. If a sufferer is lucky enough to find a sympathetic doctor, such as an ENT or an allergy and asthma specialist willing to prescribe a NasoNeb, even if just to use with saline solution, that might be beneficial. It is very doubtful that any doctor would prescribe antibiotics or antifungal meds without first establishing that there is indeed an infection.

  1. 0.9% Sodium Chloride Solution, USP (Sterile, Non-Pyrogenic)
  2. Betamethasone (Brand name: Celestone Soluspan) - a synthetic glucocorticoid used as an anti-inflammatory to help reduce swelling within the sinuses and nasal passages, redness and allergic reactions. It is used for treating severe asthma, severe allergies, rheumatoid arthritis, ulcerative colitis, certain blood disorders, lupus, MS, and certain eye and skin conditions.
  3. Levofloxacin (Brand name: Levaquin) - an antibacterial in the fluoroquinoione class of antibiotics. Indications for its use are treatment for sinusitis caused by susceptible bacteria, including: Streptococcus pneumoniae, Haemophilus influenza, or Moraxella catarrhalis.
  4. Mometasone (Brand name: Nasonex) - a synthetic nonfluorinated corticosteroid used as an anti-inflammatory, helps reduce swelling, redness and allergic reactions within the sinuses and nasal passages.
  5. itraconazole (Brand name: Sporanox) - antifungal infections that begin in the lungs and can spread through the body. "Itraconazole oral solution is used to treat yeast infections of the mouth and throat and suspected fungal infections in patients with fever and certain other signs of infection. Itraconzale is in a class of antifungals called trazoles, which works by slowing the growth of fungi that cause infection."
  6. clarithromycin (Brand name: Biaxin) - antibiotics used to treat certain infections caused by bacteria, such as pneumonia (a lung infection), bronchitis (infection of the tubes leading to the lungs), and infections of the ears, sinuses, skin, and throat.
  7. clindamycin (Brand name: Cleocin) - a lincosamide antibiotic used to treat certain types of bacterial infections, including infections of the lungs, skin, blood, female reproductive organs, and internal organs.
  8. ceftriaxone (Brand names: Rocephin, Rocephin IM Convenience Kit (obsolete), Rocephin ADD-Vantage) - is a cephalosporin antibiotic that is effective against gram-positive and gram negative bacteria.It is used to "treat many kinds of bacterial infections, including severe or life-threatening forms such as meningitis."

MY PERSONAL EXPERIENCE AND EFFECTIVE TREATMENT: Since I suffer from allergies and asthma, I tend to have excess nasal secretions, including constant post nasal drip. During flareups, I also have congestion in my bronchioles and lungs. Thanks to the good treatment provided to me by my Allergy and Asthma physician, I believe that I have controlled not only my allergies and asthma, but also, my nasal halitosis. She has prescribed for me a very effective nasal treatment that I use whenever I notice that I may have nasal halitosis.

My doctor prescribed for me the NasoNeb Nasal Nebulizer covered by most insurance carriers in the US. It has helped me tremendously with my allergies and with halitosis. When I have a sinus infection, my doctor prescribes antibiotics seen on this video which can be applied locally with this nasal nebulizer, thus avoiding systemic treatment. Also, anti-fungal medication can be used with this nebulizer. When I have allergies that produce sinus swelling, she prescribes one of the corticosteroid that is applied locally, also seen on this video, that brings down swelling.

But when I only have nasal halitosis without allergies or infection, usually resulting from foods I've eaten, odorous chemical compounds (VOCs) tend to build up in my sinus mucous membrane resulting in nasal halitosis, so I use the NasoNeb with only saline solution a couple of times a day for a few days, or even once a day for a few days, and it helps almost immediately.

I must say, it takes some getting use to because the treatment involves spitting out your mouth the medication/saline solution that went in through your nose. But it works exceptionally well without having to take oral medication that works systemically.

halitosis research
María de la Torre
Founder and Executive Director

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