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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

Scroll down and select country

MEBO Map Testing & Meetups

Full details :
want listed ? contact

MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Join/Watch the weekly
BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

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MEBO Metabolic Malodor Survey (international) for Dr Hazen click here
click to Read more/less

survey for ANYONE who identifies with METABOLIC MALODOR

begun : Oct20
end : no ending for now

Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

This is a GOOGLE FORMS survey

short url for survey :

current participants : 113 (update 18dec20)

Monday, June 16, 2008

Could leaky gut be a factor in Fecal Body Odor ?

It's unknown if something like 'leaky gut' (gut permeability) could be a factor in something like, for instance 'fecal body odor'. Research into 'leaky gut' in general seems lacking, but sometimes interesting (unrelated) research is published. For instance, this 1999 paper about only alcoholics with 'leaky gut' having cirrhosis ...
Leaky gut in alcoholic cirrhosis: a possible mechanism for alcohol-induced liver damage.

Two functions of the gut wall are to physically act as a sieve (to not allow molecules too big to be absorbed into the portal vein), and also to absorb suitable sized molecules in a controlled manner (often actively, as well as passively).

In the case of 'leaky gut', it is proposed that for some reason the junctions of the cells are not properly joined, and molecules too large are then allowed through the gaps into the portal vein.

Ironically, if the 'absorption' system through the gut wall cells is also interfered with for some reason, for example irritation, someone can then have potential 'malabsorption' as well as leaky gut.

The current common test for leaky gut usually tests both for 'leaky gut' and also malabsorption, using 2 sugars, lactulose (a large molecule), and mannitol (a small molecule). The other alternative common test is the polyethylene glycol (PEG) test

some leaky gut explanations :

from an Autism research unit at Sunderland University :
Leo Galland article :
Dr Myhill article :

(example) pubmed search result


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