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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

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MEBO Map Testing & Meetups

Full details :
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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Join/Watch the weekly
BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

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MEBO Metabolic Malodor Survey (international) for Dr Hazen click here
click to Read more/less

survey for ANYONE who identifies with METABOLIC MALODOR

begun : Oct20
end : no ending for now

Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

This is a GOOGLE FORMS survey

short url for survey :

current participants : 113 (update 18dec20)

Sunday, August 17, 2008

Parasites: ruling them out

not to be used as advice
post refers to intestinal parasites only.
tests referred to are clinical laboratory tests

With bloodborne body/halitosis, the 2 obvious lines of investigation would seem to be the detox enzymes, and the gut ecology (and gut function). Since bloodborne body odor is an unknown/unrecognised condition (apart from trimethylaminuria and one paper on dimethylglycinuria), it would seem that ruling things out would seem an option. It would be better if these sorts of tests were done as a group ina co-operative way with the intention of defining the syndrome (for instance as medical studies are done), but this doesn't currently seem an option.

With regards gut ecology, one area seemingly worth investigating would be factors that cause gut dysbiosis. Most fecal body odor sufferers seem to feel they have a gut issue, for instance. The 3 groups of potential pathogenic (disease causing) microbes would seem to be: bacteria, fungi, parasites.

This post will look at parasites. On the one hand, they are probably understimated, on the other hand it seems unlikely they are a 'necessary' part of, for instance, fecal body odor 'syndrome'. There are 2 types of parasites in general; helminths and protozoa. Helminths are what we think of as 'worms', whereas protozoans are single-celled. There are all sorts of both types.

Also, with regards being 'pathogenic', some are easily regarded as such (probably termed category B pathogens), whereas some are regarded as 'low-grade' pathogenic or even regarded as being 'asymptomatic' (not disease causing) in many carriers, or their 'pathogenic' classification is still debated (for instance, the protozoa blastocystis. Giardia has not been unquestionably regarded a pathogenic parasite until the last few decades). You can think of these classifications as the same way scientists currently debate global warming.

There are tests available without seeing a doctor to rule out parasites. However, one test cannot be deemed as totally reliable on the 'false negative' side (false negative means the negative may have been wrong). It could probably be assumed false positives are unlikely. It must also be understood that the established medical system may not test for 'grey area' parasites (e.g. 20 years ago they wouldn't have tested for giardia. They wait until they are officially deemed 'parasites' by their established peer group), whereas more forward-thinking labs will (for instance, blastocystis). So if you tested, it would be wise to know what they were looking for.

Whatever anyone does regarding this, they do so under their own responsibility.

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