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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

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MEBO Map Testing & Meetups

Full details :
want listed ? contact

MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Join/Watch the weekly
BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

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MEBO Metabolic Malodor Survey (international) for Dr Hazen click here
click to Read more/less

survey for ANYONE who identifies with METABOLIC MALODOR

begun : Oct20
end : no ending for now

Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

This is a GOOGLE FORMS survey

short url for survey :

current participants : 113 (update 18dec20)

Tuesday, August 26, 2008

probiotics: local civilians and special forces ?

This is an attempt to understand why so many different types of probiotics are available.

When taking probiotics, the most obvious type would seem to be the main friendly 'locals' of the human gut. Usually thats thought to be lactobacillus acidophilus (small intestine), and bifidobacteria (longum ? bifidum ? ) in the colon. And yet there are lots of other types of probiotics on the market.

One possibly theory is that, if you regard your 'gut' as the local neighborhood (your gut flora can weigh around 3 lbs), then the 2 types mentioned above are the 'locals'. With dysbiosis, the neighborhood has been taken over and the locals driven out. Possibly some of the other types of probiotics marketed are supposed to be 'special forces' that can fight the 'baddies' much more effectively. Or perhaps it's just that they can patent their own newly found strains of probiotic and make more money.

One example is Saccharomyces boulardii. This is a yeast. You would expect it to be the worst thing to take to fight candida in the gut. And yet it is promoted as such. One theory suggested is that it is so good at out-competing candida that it aggressively wins back the neighborhood. Florastor is one such brand. Dr Hyman suggests taking this along with the normal human probiotics.

Other examples are lactobacillus sporogenes, Lactobacillus casei Shirota (the probiotic in yakult. Presumably patented), rhamnosus, etc etc.

So perhaps one categorisation of probiotics could be the 'friendly locals' and 'special forces' (or perhaps not).

None of the above should be regarded as recommendation.

Dr Hymans probiotic suggestions for IBS:

I don't usually recommend brands, but for these probiotics the quality varies so much that I suggest taking two specific brands. Take one packet of VSL3 ( twice a day for 1 to 2 months, which has over 450 billion organisms per packet. I also recommend one to two packets of Florastor ( twice a day for 2 months, a special probiotic that helps further normalize gut function.


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