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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

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MEBO Karen
at UK Findacure conf 2020

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MEBO Map Testing & Meetups

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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

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Denver TMAU Test Lab survey click here
click to Read more/less

USA survey for anyone who wants to improve Denver TMAU test

begun : Dec22
end : no ending for now

A trainee genetic counselor is working at the Denver TMAU test lab. Probably as part of her training. As a project she wishes feedback on any aspect of the Denver TMAU test and process. You can fill in the survey and/or email her (email address is in survey). It's meant for USA people, but perhaps others can give their view too (as we have so few opportunities).

quote from her rareconnect post

"Hello all! I wanted to make you aware of a research study being conducted to better understand the experience and needs of individuals with trimethylaminuria with a goal of being able to create improved patient and healthcare provider education materials. Any participation is completely voluntary and all responses remain confidential. Feel free to use the contact information within the link with any questions or share the survey with others with TMAU."

see this post for more details

Tuesday, August 26, 2008

probiotics: local civilians and special forces ?

This is an attempt to understand why so many different types of probiotics are available.

When taking probiotics, the most obvious type would seem to be the main friendly 'locals' of the human gut. Usually thats thought to be lactobacillus acidophilus (small intestine), and bifidobacteria (longum ? bifidum ? ) in the colon. And yet there are lots of other types of probiotics on the market.

One possibly theory is that, if you regard your 'gut' as the local neighborhood (your gut flora can weigh around 3 lbs), then the 2 types mentioned above are the 'locals'. With dysbiosis, the neighborhood has been taken over and the locals driven out. Possibly some of the other types of probiotics marketed are supposed to be 'special forces' that can fight the 'baddies' much more effectively. Or perhaps it's just that they can patent their own newly found strains of probiotic and make more money.

One example is Saccharomyces boulardii. This is a yeast. You would expect it to be the worst thing to take to fight candida in the gut. And yet it is promoted as such. One theory suggested is that it is so good at out-competing candida that it aggressively wins back the neighborhood. Florastor is one such brand. Dr Hyman suggests taking this along with the normal human probiotics.

Other examples are lactobacillus sporogenes, Lactobacillus casei Shirota (the probiotic in yakult. Presumably patented), rhamnosus, etc etc.

So perhaps one categorisation of probiotics could be the 'friendly locals' and 'special forces' (or perhaps not).

None of the above should be regarded as recommendation.

Dr Hymans probiotic suggestions for IBS:

I don't usually recommend brands, but for these probiotics the quality varies so much that I suggest taking two specific brands. Take one packet of VSL3 ( twice a day for 1 to 2 months, which has over 450 billion organisms per packet. I also recommend one to two packets of Florastor ( twice a day for 2 months, a special probiotic that helps further normalize gut function.


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