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MEBO TMAU TESTING CURRENTLY SUSPENDED INDEFINITELY

MEBO - UBIOME study 2018

'PRESS RELEASE'

NCT03582826
ClinicalTrials.gov

MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production
& PATM

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person

NO LONGER RECRUITING

Participation info : LINK English

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Full details : https://goo.gl/TMw8xu
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TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study
NCT02683876

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned


Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
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Blog Archive

MEBO Research Clinical Trials

Click here to read details of the MEBO Clinical Trials
NCT03582826 - Ongoing not recruiting
Microbial Basis of Systemic Malodor and PATM Conditions (PATM)
United States 2018 - ongoing

NCT02683876 - Completed
Exploratory Study of Relationships Between Malodor and Urine Metabolomics
Canada and United States 2016 - ongoing

NCT03451994 - Completed
Exploratory Study of Volatile Organic Compounds in Alveolar Breath
United Kingdom and United States 2013 - ongoing

NCT02692495 - Completed
Evaluation of Potential Screening Tools for Metabolic Body Odor and Halitosis
United Kingdom 2009 - 2012

Friday, December 5, 2008

A word from Dr. Richard S. Lord, PhD: of Metametrix

Richard S. Lord, PhD, director of the Department of Science and Education at Metametrix Clinical Laboratory, has helpfully posted a reply to the post on his 'GIfx' presentation video posted in this blog recently. At the moment (until someone investigates), it seems likely gut dysbiosis may be a factor (or the factor) in some metabolic body odor cases, especially the fecal/gas/sewage/garbage/rotten egg/etc type that seems the most common type. Metametrix specialise in gut dysbiosis testing, and other metabolic types of testing. Thank you from the community Dr Lord, for taking the time to post.

Metametrix GIfx test will likely give society the best definition of 'dysbiosis(es)' yet, and the most up-to-date understanding of gut ecology so far, although the test has not been available that long, so it is very early days. They detect the state of the gut ecology using DNA detection of microbes in stool samples. This will likely become the standard way to test stool samples for microbiota evaluation. The old fashioned way, still probably commonly used, meant having to 'culture' microbes from stool samples in the lab. The advantages of DNA testing are explained on the GIfx site

Having noticed this new posting of the presentation, I can add that a publication is now being prepared to report our finding of distinct groupings of predominant genera among the patient stool specimens that have been examined. Specific genera tend to appear at high levels as one of three clusters. When any one of the clusters dominates the fecal bacteria population, higher incidences of opportunistic bacteria are found. This finding represents another step in the unfolding story of what specific patterns constitute states of dysbiosis.

From routine clinical evaluations of patients, we are amassing a very large database of results using the DNA-based methods to analyze stool specimens. Doctors who use the testing are learning how to evaluate the significance of each abnormality (such as the presence of a parasite of pathogen) in relation to the total picture, including the balance of predominant anaerobic bacteria.
This is an exciting time for scientist and clinicians who have long sought to understand how the billions of microbes that live within us contribute to human health and disease. Stay tuned as the story continues to unfold.

Richard Lord

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