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MEBO TMAU TESTING CURRENTLY SUSPENDED INDEFINITELY

MEBO - UBIOME study 2018

'PRESS RELEASE'

NCT03582826
ClinicalTrials.gov

MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production
& PATM

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person

NO LONGER RECRUITING

Participation info : LINK English

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Full details : https://goo.gl/TMw8xu
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TMAU UK end total:262
TMAU UK ends 23/01/20
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USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study
NCT02683876

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned


Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
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London TMAU meeting with Prof Liz Shephard
19th Oct 11am - 1pm
St Mary's Hospital
Praed St, Paddington
London W2 1NY
click to read more
more details : karen.james@meboresearch.org

MEBO Research Clinical Trials

Click here to read details of the MEBO Clinical Trials
NCT03582826 - Ongoing not recruiting
Microbial Basis of Systemic Malodor and PATM Conditions (PATM)
United States 2018 - ongoing

NCT02683876 - Completed
Exploratory Study of Relationships Between Malodor and Urine Metabolomics
Canada and United States 2016 - ongoing

NCT03451994 - Completed
Exploratory Study of Volatile Organic Compounds in Alveolar Breath
United Kingdom and United States 2013 - ongoing

NCT02692495 - Completed
Evaluation of Potential Screening Tools for Metabolic Body Odor and Halitosis
United Kingdom 2009 - 2012

Saturday, January 24, 2009

Hair testing

When metabolic body odors and metabolic halitosis finally get attention from the health system, stage one will be trying to define what the problem is through testing. The technology is probably readily available in labs across the countries (say, at metabolism units in hospitals), it's a case of getting them to test for the metabolites (in the way that a very few test for trimethylamine).

"Drug and drug metabolite(s) are incorporated into the hair matrix from the bloodstream following drug use. Hair drug testing detects drugs that are embedded in the hair"

Labcorp site
Once that stage is reached, it's a question of how to test the patient. There are a few various ways. The most obvious would be testing for volatile organic compounds in urine, blood or breath. Another new(ish) way of testing is from hair samples.

This post is about hair testing. Currently drug and alcohol detection labs seem to use the various ways to detect drug/alcohol and are the most obvious labs on google searches of "hair testing". It's unclear if the health-system 'advisors' back their claims.

Taking the labs claims as accurate without question, the advantage of hair testing seems to be that it can detect compounds accumulated over days/weeks. Unfortunately no-one tests for likely 'smelly' compounds currently. A 'metabolic body odor' profiling test. Some check mineral status. Hair testing would be no use as 'spot tests'. For trimethylaminuria, first thoughts are that it would maybe be able to detect trimethylamine, but not trimethylamine-oxide.

Overall, the concept sounds useful but it's unknown how accurate the method of testing is currently regarded.


random links :
wikipedia : hair testing
Labcorp hair-testing lab for drug/alcohol detection
Pubmed 2001 paper on hair testing
Letter of reply from a lab re the Pubmed paper
Society of Hair Testing

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