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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

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MEBO Map Testing & Meetups

Full details :
want listed ? contact

MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Join/Watch the weekly
BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

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MEBO Metabolic Malodor Survey (international) for Dr Hazen click here
click to Read more/less

survey for ANYONE who identifies with METABOLIC MALODOR

begun : Oct20
end : no ending for now

Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

This is a GOOGLE FORMS survey

short url for survey :

current participants : 113 (update 18dec20)

Tuesday, March 3, 2009

Great Plains laboratory and the other main dysbiosis testing labs in the USA

In the USA, perhaps the 3 best known 'niche' labs for dysbiosis are the following:

Genova Diagnostics
Great Plains lab

In this post, we will look briefly at Great Plains laboratory. Of the 3 above, Genova and Metametrix seem closely associated with Functional Medicine, whereas it's unclear where Great Plains affiliation lies (it looks like a stand-alone company). The Great Plains founder, Dr William Shaw, was interested in gas chromatography-mass spectrometry, and noticed that some patients had high levels of metabolites that he associated with yeast. his lab associates 'tartaric acid' with gut candidiasis. The lab itself seems geared towards autism in particular (autistic people often have 'bowel' issues). An initial impression is that he could be regarded as a maverick 'conservative' physician. you can see his introductory video here.

His expertise seems to be from a gas chromatography-mass spectrometry background, and so his lab is very interested in metabolites. But they do do the full range that someone would expect from these type of investigative niche labs (immune tests, metabolite tests etc). His lab hold workshops and online conferences.

It's not known if there are any differences in the labs or if one or the other is more preferable. Perhaps at this point, the only real way of knowing would be for someone rich to do the same test in all 3 labs.

One good thing about Great Plains is that they seem to be allowing people to order the tests direct, rather than using the old 'physician knows best' principle (which in truth seems like a job-protection blocker rather than best for the patient). This is a first impression, when looking at the website to order the tests. Metametrix also allow direct testing through 3rd parties such as

None of the above labs are likely aware of systemic body odor and particularly fecal body odor of course. Even amongst niche labs and functional medicine, the problem is still not recognised

Since yeast is often mentioned as a possible factor in fecal body odor on the body odor forums, it's interesting to read Dr Shaw's views on gut yeast infection. This article may be tailored towards autism in particular, but perhaps fecal odor sufferers have a similar problem in that for some reason their gut always has problems controlling the gut flora. In the article, Dr Shaw hypothesizes that some people perhaps for some reason do not have the normal checks and balances that stop the gut flora going bad, and external help may be needed for maintenance.

The 3 main groups of microbes that are mainly thought to cause gut dysbiosis are yeast (probably candida in particular), bacteria (both bad, or displaced or overgrowth) and parasites.

related links

Dr Shaw 1995 medical paper on a gut yeast infection case

comparison of analytes tested in their dysbiosis organic acids tests
Genova: (note) this is their full organic acid test
Metametrix: dysbiosis test only
Great Plains: dysbiosis test only


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