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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info: https://youtu.be/811v7RLXP9M
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MEBO TMAU TESTING DISCONTINUED
(2012-2017)

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MEBO - UBIOME study 2018

'PRESS RELEASE'

NCT03582826
ClinicalTrials.gov

MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production
& PATM

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person

NO LONGER RECRUITING

Participation info : LINK English

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BO Sufferers Podcasts

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Petitions

TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study
NCT02683876

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned


Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
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Denver TMAU Test Lab survey click here
click to Read more/less

USA survey for anyone who wants to improve Denver TMAU test

begun : Dec22
end : no ending for now

A trainee genetic counselor is working at the Denver TMAU test lab. Probably as part of her training. As a project she wishes feedback on any aspect of the Denver TMAU test and process. You can fill in the survey and/or email her (email address is in survey). It's meant for USA people, but perhaps others can give their view too (as we have so few opportunities).

quote from her rareconnect post

"Hello all! I wanted to make you aware of a research study being conducted to better understand the experience and needs of individuals with trimethylaminuria with a goal of being able to create improved patient and healthcare provider education materials. Any participation is completely voluntary and all responses remain confidential. Feel free to use the contact information within the link with any questions or share the survey with others with TMAU."

see this post for more details

https://www.meboblog.com/2023/01/denver-tmau-test-survey-tbc-who-it-is.html

Tuesday, November 3, 2009

New FMO3 paper from Japan



FMO3 research is always of interest to the blog, given that it is the enzyme that neutralizes trimethylamine in humans, and also deals with 1,000s of other smelly compounds (which contain a sulfur, nitrogen or phosphate).

The abstract does not contain much information on the paper, so it is unknown how significant the paper is. Presumably it is only more 'proof' of previous research. It is of interest that they mention 9 'novel' TMAU cases were diagnosed amongst self-reported volunteers, probably indicating how the problem is underestimated, given the current list of 'FMO3 DNA baddies'.


This Japanese lab, Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, has a history of Trimethylaminuria research and testing, and perhaps Japanese members of the community would be able to test for TMAU there in Japan.

この日本語研究室、研究室薬物動態、昭和薬科大学、そして社会の、おそらく日本のメンバーTMAUのため、日本でテストすることができるだろうTMAU研究の歴史があります。

http://www.shoyaku.ac.jp/j-home/01kenkyu/lab/doutai/index.html

Update:

It does look as if this university lab does do the TMAU urine test. Here is the Professor's own website :

Trimethylamine testing website in Japanese
Japanese TMAU test site in google-translation to English
Professor Yamazaki's TMAU website in google-translation
日本語トリメチルアミン尿症のテストサイト
教授山崎昭和大学トリメチルアミン尿症のウェブサイト

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