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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
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Blog Archive

MEBO Research Clinical Trials

Click here to read details of the MEBO Clinical Trials
NCT03582826 - Ongoing not recruiting
Microbial Basis of Systemic Malodor and PATM Conditions (PATM)
United States 2018 - ongoing

NCT02683876 - Completed
Exploratory Study of Relationships Between Malodor and Urine Metabolomics
Canada and United States 2016 - ongoing

NCT03451994 - Completed
Exploratory Study of Volatile Organic Compounds in Alveolar Breath
United Kingdom and United States 2013 - ongoing

NCT02692495 - Completed
Evaluation of Potential Screening Tools for Metabolic Body Odor and Halitosis
United Kingdom 2009 - 2012

Tuesday, April 27, 2010

Tester 7 : MeBO-Biolab gut dysbiosis study

We are happy to announce the results of Tester 7 in our MeBO-Biolab gut dysbiosis study. This one is particularly interesting since the volunteer is from the other side of the world (Philippines). We were not sure if it would be possible for her to test, but after consultation with Biolab it was decided that there would likely be a big enough time window for the samples to be transported without deterioration apart from the d-lactate test.

The study is an unofficial one looking at a few various biomarkers of 'gut dysbiosis'. It is not conclusive, but rather just to look at a few biomarkers to see if there is any pattern. Of particular interest is the gut fermentation test since it tests for ethanol, in this case a by-product of yeast fermentation in the small intestine; and also gut permeability, which checks for 'leaky gut' as well as under-absorption. So it does seem possible people can test ok from overseas, providing shipping is relatively speedy, and drawing blood is possible (i.e. phlebotomy). We have also added the vitamin B2 blood test to our list of tests, since B2 is a co-vitamin in proper FMO3 function.

Tester 7
mid 40's
Odor problem:
Halitosis (systemic sourced) for 5 years. Rotten & chemical smells
Gut problems
Used to have IBS but was corrected by probiotics. Feels that probiotics help.
Other comments
Has a hard time digesting vegetables. Sometimes craves simple carbohydrates and feels that sulfur foods and stress provoke the problem
Trimethylaminurianot tested
Results :
Tester 7
Gut FermentationEthanol is 'mildly' raised at 69 (under 22 is normal).
body odor gut fermentation tester 7
Gut permeability Normal
body odor gut permeability tester 7



Notes on results :

The tester seems to have an issue with yeast overgrowth in the small intestine (the test is specially timed to check for alcohols and fatty acids produced in the small intestine) and also was positive for the indicans test, which implies a possible problem with gut bacteria feeding off protein. The 'ethanol/yeast' result is quite common amongst our testers so far, often being the 'dysbiosis' marker in the group of tests to show positive.

Thanks again to all the participants. Anyone wishing to participate would need to pay their own test costs (£170 for all tests). You can join the study by filling out the gut dysbiosis questionaire
Whilst the results should not be considered conlcusively proving anything, it's seen as a starting point in using tests to see what is going on in the body, and perhaps a pattern will show up that would be worth considering further. It is suggested that anyone who feels they have a systemic body odor problem should also test for TMAU, although we cannot arrange that. Anyone who has tested for TMAU is also welcome to participate in the study. We hope to get around 15 testers at least. Currently tester 8 is testing.


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