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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

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MEBO Map Testing & Meetups

Full details :
want listed ? contact

MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Join/Watch the weekly
BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

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MEBO Metabolic Malodor Survey (international) for Dr Hazen click here
click to Read more/less

survey for ANYONE who identifies with METABOLIC MALODOR

begun : Oct20
end : no ending for now

Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

This is a GOOGLE FORMS survey

short url for survey :

current participants : 113 (update 18dec20)

Tuesday, April 27, 2010

Tester 7 : MeBO-Biolab gut dysbiosis study

We are happy to announce the results of Tester 7 in our MeBO-Biolab gut dysbiosis study. This one is particularly interesting since the volunteer is from the other side of the world (Philippines). We were not sure if it would be possible for her to test, but after consultation with Biolab it was decided that there would likely be a big enough time window for the samples to be transported without deterioration apart from the d-lactate test.

The study is an unofficial one looking at a few various biomarkers of 'gut dysbiosis'. It is not conclusive, but rather just to look at a few biomarkers to see if there is any pattern. Of particular interest is the gut fermentation test since it tests for ethanol, in this case a by-product of yeast fermentation in the small intestine; and also gut permeability, which checks for 'leaky gut' as well as under-absorption. So it does seem possible people can test ok from overseas, providing shipping is relatively speedy, and drawing blood is possible (i.e. phlebotomy). We have also added the vitamin B2 blood test to our list of tests, since B2 is a co-vitamin in proper FMO3 function.

Tester 7
mid 40's
Odor problem:
Halitosis (systemic sourced) for 5 years. Rotten & chemical smells
Gut problems
Used to have IBS but was corrected by probiotics. Feels that probiotics help.
Other comments
Has a hard time digesting vegetables. Sometimes craves simple carbohydrates and feels that sulfur foods and stress provoke the problem
Trimethylaminurianot tested
Results :
Tester 7
Gut FermentationEthanol is 'mildly' raised at 69 (under 22 is normal).
body odor gut fermentation tester 7
Gut permeability Normal
body odor gut permeability tester 7



Notes on results :

The tester seems to have an issue with yeast overgrowth in the small intestine (the test is specially timed to check for alcohols and fatty acids produced in the small intestine) and also was positive for the indicans test, which implies a possible problem with gut bacteria feeding off protein. The 'ethanol/yeast' result is quite common amongst our testers so far, often being the 'dysbiosis' marker in the group of tests to show positive.

Thanks again to all the participants. Anyone wishing to participate would need to pay their own test costs (£170 for all tests). You can join the study by filling out the gut dysbiosis questionaire
Whilst the results should not be considered conlcusively proving anything, it's seen as a starting point in using tests to see what is going on in the body, and perhaps a pattern will show up that would be worth considering further. It is suggested that anyone who feels they have a systemic body odor problem should also test for TMAU, although we cannot arrange that. Anyone who has tested for TMAU is also welcome to participate in the study. We hope to get around 15 testers at least. Currently tester 8 is testing.


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