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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

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MEBO Karen
at UK Findacure conf 2020

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MEBO Map Testing & Meetups

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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

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Denver TMAU Test Lab survey click here
click to Read more/less

USA survey for anyone who wants to improve Denver TMAU test

begun : Dec22
end : no ending for now

A trainee genetic counselor is working at the Denver TMAU test lab. Probably as part of her training. As a project she wishes feedback on any aspect of the Denver TMAU test and process. You can fill in the survey and/or email her (email address is in survey). It's meant for USA people, but perhaps others can give their view too (as we have so few opportunities).

quote from her rareconnect post

"Hello all! I wanted to make you aware of a research study being conducted to better understand the experience and needs of individuals with trimethylaminuria with a goal of being able to create improved patient and healthcare provider education materials. Any participation is completely voluntary and all responses remain confidential. Feel free to use the contact information within the link with any questions or share the survey with others with TMAU."

see this post for more details

Wednesday, April 28, 2010

MeBO-Biolab gut dysbiosis study : Brief summary of results so far

This is a brief look at the results so far in the MeBO-Biolab gut dysbiosis study, looking at certain biomarkers in volunteers who feel they have a systemic body odor or halitosis problem. The main trend is that 5 out of 7 were higher than normal for ethanol, which in the test is thought to be produced by yeast fermentation in the small intestine. We are told by Biolab that the highest results for abnormal ethanol in their history is around 180-200. An average abnormal is around 80. As can be seen of our group, 2 of the testers were considerably high for ethanol. Gut permeability (a high result means 'leaky gut') did not seem to be as common or bad as expected overall. Only 2 were positive for indicans, and only 1 person for d-lactate (quite severely). Tester 5 was deficient for B2, which is a cofactor in FMO3 function. We have added this test since then to the study

An 8th person is currently testing, with a couple more showing an interest. We hope to get to around 15 volunteers minimum, and thank all volunteers for paying for their own tests and being part of the study.

testergut fermentationcommentsgut permeabilitycommentsindicansd-lactate under60b2 (normal 1.2 - 1.3)TMAU test
1ethanol not detectednormalnormalslight underpermeabilitynormalnormalnot donenormal
2ethanol 140 (under22 normal)high ethanolincrease 374-506slight increase between 374-506normal156 very highnot donenormal
3ethanol 66mild high ethanolraised after 374slightly raised after 374 onwardspositive2 (normal)not donenot tested
4ethanol 4normalhigh between 330-550quite a big risenormalnormalnot donenot tested
5ethanol 134high ethanolnormal normal but rising at the endnormal2 (normal)1.81 (deficient)normal
6ethanol 22borderline raised ethanolincreased at 242very strange high peak at 242negative
8 (normal)not donenot tested
7ethanol 69mild high ethanolnormal
positivenot donenot donenot tested

Anyone who feels they have a systemic body odor or systemic sourced halitosis problem are our main target as volunteers for the study. The 5 tests would cost £170 in total. Anyone who would like to test can fill in the brief survey to join if they wish. The intention is to kickstart exploration of systemic body odors and halitosis via biomarker testing, in this case looking at a few gut dysbiosis markers. In the end, an abnormal result does not mean it is responsible for your problem, only that it may be a factor to consider :
MeBO-Biolab gut dysbiosis questionaire


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