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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info: https://youtu.be/811v7RLXP9M
MEBO Karen
at UK Findacure conf 2020

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MEBO TMAU TESTING DISCONTINUED
(2012-2017)

MEBO Map Testing & Meetups


Full details : https://goo.gl/TMw8xu
want listed ? contact info@meboresearch.org

MEBO - UBIOME study 2018

'PRESS RELEASE'

NCT03582826
ClinicalTrials.gov

MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production
& PATM

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person

NO LONGER RECRUITING

Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
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BO Sufferers Podcasts

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Petitions

TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study
NCT02683876

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned


Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
EURORDIS and
NORD Member Organization
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MEBO survey for Dr Hazen click here
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Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

MEBO Research Clinical Trials

Wednesday, April 28, 2010

MeBO-Biolab gut dysbiosis study : Brief summary of results so far

This is a brief look at the results so far in the MeBO-Biolab gut dysbiosis study, looking at certain biomarkers in volunteers who feel they have a systemic body odor or halitosis problem. The main trend is that 5 out of 7 were higher than normal for ethanol, which in the test is thought to be produced by yeast fermentation in the small intestine. We are told by Biolab that the highest results for abnormal ethanol in their history is around 180-200. An average abnormal is around 80. As can be seen of our group, 2 of the testers were considerably high for ethanol. Gut permeability (a high result means 'leaky gut') did not seem to be as common or bad as expected overall. Only 2 were positive for indicans, and only 1 person for d-lactate (quite severely). Tester 5 was deficient for B2, which is a cofactor in FMO3 function. We have added this test since then to the study

An 8th person is currently testing, with a couple more showing an interest. We hope to get to around 15 volunteers minimum, and thank all volunteers for paying for their own tests and being part of the study.

testergut fermentationcommentsgut permeabilitycommentsindicansd-lactate under60b2 (normal 1.2 - 1.3)TMAU test
1ethanol not detectednormalnormalslight underpermeabilitynormalnormalnot donenormal
2ethanol 140 (under22 normal)high ethanolincrease 374-506slight increase between 374-506normal156 very highnot donenormal
3ethanol 66mild high ethanolraised after 374slightly raised after 374 onwardspositive2 (normal)not donenot tested
4ethanol 4normalhigh between 330-550quite a big risenormalnormalnot donenot tested
5ethanol 134high ethanolnormal normal but rising at the endnormal2 (normal)1.81 (deficient)normal
6ethanol 22borderline raised ethanolincreased at 242very strange high peak at 242negative
8 (normal)not donenot tested
7ethanol 69mild high ethanolnormal
positivenot donenot donenot tested

Anyone who feels they have a systemic body odor or systemic sourced halitosis problem are our main target as volunteers for the study. The 5 tests would cost £170 in total. Anyone who would like to test can fill in the brief survey to join if they wish. The intention is to kickstart exploration of systemic body odors and halitosis via biomarker testing, in this case looking at a few gut dysbiosis markers. In the end, an abnormal result does not mean it is responsible for your problem, only that it may be a factor to consider :
MeBO-Biolab gut dysbiosis questionaire

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