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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info: https://youtu.be/811v7RLXP9M
MEBO Karen
at UK Findacure conf 2020

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MEBO TMAU TESTING DISCONTINUED
(2012-2017)

MEBO Map Testing & Meetups


Full details : https://goo.gl/TMw8xu
want listed ? contact info@meboresearch.org

MEBO - UBIOME study 2018

'PRESS RELEASE'

NCT03582826
ClinicalTrials.gov

MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production
& PATM

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person

NO LONGER RECRUITING

Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
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BO Sufferers Podcasts

MEBO TMAU Videos

Petitions

TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study
NCT02683876

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned


Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
EURORDIS and
NORD Member Organization
See RareConnect

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MEBO survey for Dr Hazen click here
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Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

MEBO Research Clinical Trials

Thursday, February 23, 2012

MeBO-Biolab gut dysbiosis study : Results for volunteer 13

Project : MEBO gut dysbiosis study using selected tests from Biolab UK within a budget

Below is the results for Tester 13 in our first testing project, the gut dysbiosis study using tests offered by Biolab Clinical laboratory in London. The tests were limited to keep the costs within a certain budget, since each volunteer was paying their own costs.

Tester 13
Male, late 20's
Odor problem:
body odor for 5 years, a range of odors including fecal, gas. Believes it systemic
Gut problems
Undigested food in stools. Crave simple carbs
Other problems
Maybe fatigue
Trimethylaminuria
Not tested


Results :
Tester 13
Gut Fermentation
Normal profile

Gut permeability
Normal profile


Indicans
positive



Comment by the study overseer, MEBO Director Professor Irene Gabashvili

Young male suffering from body odor for 5 years, a range of odors including fecal.
Main findings are positive Indicans (as in 40% of sufferers), along with decreased short chain fatty acids (SCFA, decreased in 50% of sufferers) and slightly elevated 2-propanol (as in 30% of sufferers).
Results are most similar to Tester 2 although not as dramatic, also similar to Tester 6.
Tester 2 was also suffering from many odors, combinations of sulfur and ammonia, while Tester 6 complained about ammonia odor. Intestinal permeability is normal, lower than in all other testers with body odor and is resembling profiles of those complaining about halitosis.

Results consistent with bacterial overgrowth and possibly excess carbohydrate reaching the colon. Malabsorption of protein, low levels of hydrochloric acid or pancreatic insufficiency may be also possible.


body odor petition
MEBO Research

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