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Samples analyzed since June 2012 :
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Blog Archive

Wednesday, March 7, 2012

Odor originating from Metabolic Disorders


BO, Body Odor777.com, Causes of and Solutions for Body Odor, has a good list of some known metabolic body malodor disorders, including trimethylaminuria (TMAU), Hypermethioninemia (HME), Maple Syrup Urine Disease (MSUD), Phenylketunuria (PKU), Multiple Acyl-CoA Dehydrogenase Deficiency (MADD), Isovaleric Acidaemia, On the left sidebar, it lists internal causes, to name a few.

They define hypermethioninemia as,


Hypermethioninemia this condition can happen when methionine (amino acid) is not metabolized correctly in the body. Individuals with this condition may experience a fishy, sweety and fruity, rancid butter or boiled cabbage odor. It has been said that tyrosinosis-tyrosinemia is the same as hypermethioninemia.

Many if not most of the conditions noted in this list area considered serious diseases, and some are life threatening. We wonder if perhaps sufferers have elevated levels of one or more of the volatile organic compounds (VOCs), while still within the normal range; and the combination of these could possibly produce a strange odor that many describe, such as garbage, sewer, fecal, or burnt odor. This is what MEBO Research will attempt to study in the Alveolar Breath Research Study soon to be launched, as well as with our methionine test in London.

On the left sidebar of the BO777 site, they have an extensive list of internal causes of body odor. It is very possible that sufferers may have a combination of sources contributing to the difficulty in controlling symptoms.

What this site lacks are reference to published papers, so the reader is encouraged to do further research into these conditions from reliable, professional journals.

See other posts in this blog:
  1. Phenylketonuria and Maple Syrup Urine disease. Recognised bloodborne odor problems
  2. 1983 Paper: Profiles of Urinary Volatiles from 3 'odorous' Metabolic Disorders
María

María de la Torre
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