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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

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MEBO Map Testing & Meetups

Full details :
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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Join/Watch the weekly
BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect

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Blog Archive

MEBO Research Clinical Trials

Click here to read details of the MEBO Clinical Trials
NCT03582826 - Ongoing not recruiting
Microbial Basis of Systemic Malodor and PATM Conditions (PATM)
United States 2018 - ongoing

NCT02683876 - Completed
Exploratory Study of Relationships Between Malodor and Urine Metabolomics
Canada and United States 2016 - ongoing

NCT03451994 - Completed
Exploratory Study of Volatile Organic Compounds in Alveolar Breath
United Kingdom and United States 2013 - ongoing

NCT02692495 - Completed
Evaluation of Potential Screening Tools for Metabolic Body Odor and Halitosis
United Kingdom 2009 - 2012

Monday, December 1, 2008

The Scent of Eros - a hormonal explanation of certain Body Odor

In their book, 'The Scent of Eros', the authors, Kohl and Francoer discus how hormones, androgens, estrogens, and progesterone, affect human body odor in a healthy body that does not suffer from metabolic body odor.

In the Chapter, Making Human Pheromones, they discuss the important role pheromones play in activating the genes in hormone-secreting nerve cells that control sexual development and behavior.

Men produce more and stronger body odor than women because androgens are the predominant sex hormone in males. Also, most males have a particular type of odor-producing bacteria on the skin. Some women have this same bacteria, but their lower levels of androgens combine with levels of estrogens and progesterone dominate in different phases of their menstrual cycle, so even the women with the skin bacteria characteristic of males do not have a strong male body odor. The shifting balance of estrogens and progesterone during the menstrual cycle is also responsible for cyclic changes in women's odor.

It appears that hormone levels, controlled by our genes, affect the intensity of body odor caused by a bacteria on the skin. If we add to this equation a metabolic condition, also controlled by our genes, that adds volatile compounds, like TMA and others, then it would appear that there is a complex interplay of causes of extreme, constant or intermittent body odor. This explains why it is so difficult for someone with a metabolic condition and/or hormonal imbalance to control his or her body odor. It would appear that having a good understanding of both would provide greater management control.

google books extract from 'The Scent of Eros'


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