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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info: https://youtu.be/811v7RLXP9M
MEBO Karen
at UK Findacure conf 2020

Scroll down and select country
MEBO TMAU TESTING DISCONTINUED
(2012-2017)

MEBO Map Testing & Meetups


Full details : https://goo.gl/TMw8xu
want listed ? contact info@meboresearch.org

MEBO - UBIOME study 2018

'PRESS RELEASE'

NCT03582826
ClinicalTrials.gov

MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production
& PATM

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person

NO LONGER RECRUITING

Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Join/Watch the weekly
BO Sufferers Podcasts

MEBO TMAU Videos

Petitions

TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study
NCT02683876

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned


Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
EURORDIS and
NORD Member Organization
See RareConnect
rareconnect.org TMAU

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MEBO Metabolic Malodor Survey (international) for Dr Hazen click here
click to Read more/less

survey for ANYONE who identifies with METABOLIC MALODOR

begun : Oct20
end : no ending for now

Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

This is a GOOGLE FORMS survey

short url for survey :
https://forms.gle/vem2TjepKobYZPBu8

current participants : 113 (update 18dec20)

Monday, December 1, 2008

The Scent of Eros - a hormonal explanation of certain Body Odor

In their book, 'The Scent of Eros', the authors, Kohl and Francoer discus how hormones, androgens, estrogens, and progesterone, affect human body odor in a healthy body that does not suffer from metabolic body odor.

In the Chapter, Making Human Pheromones, they discuss the important role pheromones play in activating the genes in hormone-secreting nerve cells that control sexual development and behavior.

Men produce more and stronger body odor than women because androgens are the predominant sex hormone in males. Also, most males have a particular type of odor-producing bacteria on the skin. Some women have this same bacteria, but their lower levels of androgens combine with levels of estrogens and progesterone dominate in different phases of their menstrual cycle, so even the women with the skin bacteria characteristic of males do not have a strong male body odor. The shifting balance of estrogens and progesterone during the menstrual cycle is also responsible for cyclic changes in women's odor.

It appears that hormone levels, controlled by our genes, affect the intensity of body odor caused by a bacteria on the skin. If we add to this equation a metabolic condition, also controlled by our genes, that adds volatile compounds, like TMA and others, then it would appear that there is a complex interplay of causes of extreme, constant or intermittent body odor. This explains why it is so difficult for someone with a metabolic condition and/or hormonal imbalance to control his or her body odor. It would appear that having a good understanding of both would provide greater management control.

google books extract from 'The Scent of Eros'

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