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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

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MEBO Map Testing & Meetups

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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

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Denver TMAU Test Lab survey click here
click to Read more/less

USA survey for anyone who wants to improve Denver TMAU test

begun : Dec22
end : no ending for now

A trainee genetic counselor is working at the Denver TMAU test lab. Probably as part of her training. As a project she wishes feedback on any aspect of the Denver TMAU test and process. You can fill in the survey and/or email her (email address is in survey). It's meant for USA people, but perhaps others can give their view too (as we have so few opportunities).

quote from her rareconnect post

"Hello all! I wanted to make you aware of a research study being conducted to better understand the experience and needs of individuals with trimethylaminuria with a goal of being able to create improved patient and healthcare provider education materials. Any participation is completely voluntary and all responses remain confidential. Feel free to use the contact information within the link with any questions or share the survey with others with TMAU."

see this post for more details

Monday, December 1, 2008

The Scent of Eros - a hormonal explanation of certain Body Odor

In their book, 'The Scent of Eros', the authors, Kohl and Francoer discus how hormones, androgens, estrogens, and progesterone, affect human body odor in a healthy body that does not suffer from metabolic body odor.

In the Chapter, Making Human Pheromones, they discuss the important role pheromones play in activating the genes in hormone-secreting nerve cells that control sexual development and behavior.

Men produce more and stronger body odor than women because androgens are the predominant sex hormone in males. Also, most males have a particular type of odor-producing bacteria on the skin. Some women have this same bacteria, but their lower levels of androgens combine with levels of estrogens and progesterone dominate in different phases of their menstrual cycle, so even the women with the skin bacteria characteristic of males do not have a strong male body odor. The shifting balance of estrogens and progesterone during the menstrual cycle is also responsible for cyclic changes in women's odor.

It appears that hormone levels, controlled by our genes, affect the intensity of body odor caused by a bacteria on the skin. If we add to this equation a metabolic condition, also controlled by our genes, that adds volatile compounds, like TMA and others, then it would appear that there is a complex interplay of causes of extreme, constant or intermittent body odor. This explains why it is so difficult for someone with a metabolic condition and/or hormonal imbalance to control his or her body odor. It would appear that having a good understanding of both would provide greater management control.

google books extract from 'The Scent of Eros'


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