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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

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MEBO Map Testing & Meetups

Full details :
want listed ? contact

MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Join/Watch the weekly
BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

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MEBO Metabolic Malodor Survey (international) for Dr Hazen click here
click to Read more/less

survey for ANYONE who identifies with METABOLIC MALODOR

begun : Oct20
end : no ending for now

Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

This is a GOOGLE FORMS survey

short url for survey :

current participants : 113 (update 18dec20)

Friday, April 2, 2010

MeBO-Biolab gut dysbiosis study : tester 5 organic acid result back

Tester 5 was our 'thorough' tester, who did a greater number of tests than the standard MeBO-Biolab gut dysbiosis study, in the hope of shining some more light on the problem of systemic body odors. Her full list of results can be seen in a previous post.

It took longer than anticipated to get her organic acid test result back, but it seems to show no obvious issues. The organic acid test chosen was not as thorough as we would have liked, but factors such as cost and accessibility played a big part. Our ideal starting point for testing would be a urine test looking for 'malodorous volatile organic compounds', but we have not found a source for this test. Also a DNA test of all the xenobiotic metabolizing enzymes (including FMO3) would seem appropriate, but this would be quite expensive.

The test included 3-hydroxy-isovaleric acid, which can be an indicator for biotin deficiency and has been reported as being high in systemic body odor cases anecdotally.

Anyone wishing to participate in the MeBO-Biolab gut dysbiosis study can do so by filling out the questionaire. It would cost you £170 to do all 5 tests. The tests chosen were to look at certain gut dysbiosis markers, as well as Vitamin B2 levels (B2 is a cofactor in proper FMO3 function). The tests should be seen as a starting point in looking for answers to systemic body odors. Of particular interest is the 'ethanol' test, which is regarded as a test of yeast gut overgrowth. So far, quite a few of our testers have been positive for this.


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