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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

MEBO Private Facebook Group
to join : go to
or contact
Ubiome Gut EXPLORER : 10% OFF
Join/Watch the weekly
TMAU UP Podcasts

Videos : TMAU stories

MEBO Map Testing & Meetups

Full details :
want listed ? contact
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect

£ 943.03/GBP
$ 568.00/USD

TOTAL at today's ROE
£0.80/GBP = $1.00/USD

£1,398.07 = $1,745.14



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Blog Archive

Tuesday, August 24, 2010

Carnitine : not just choline to be avoided in TMAU diet

Those interested in TMAU are very aware that choline is to be kept minimal in the disorder, since gut bacteria can metabolize the choline, with one resulting metabolite being trimethylamine (TMA). However it may be often overlooked that another compound that can result in TMA production is carnitine.

The 'avoidance' diet strategy for TMAU mainly involves :

1. Keeping anything that can result in TMA to a minimum
obvious examples :
  • Choline (remember this is an essential nutrient though)
  • Any food with high TMA-oxide content, since the TMA-oxide is broken down to TMA in our gut (e.g. seafood)
  • Carnitine

2. Avoiding anything that inhibits the FMO3 enzyme
So far, only indoles in cruciferous veg have been proven to inhibit the enzyme. It's possible more foods are to be discovered.

In humans, most carnitine in the diet is derived from lysine and methionine, so anything high in these 2 amino acids will naturally result in the most carnitine. This shows how difficult it is to avoid, given that lysine and methionine are in many foods. 2 common main sources are red meat and in the whey portion of dairy foods. But red meat is the most abundant food by far, as can be seen in the table in this page : Office of Dietary Supplements info on carnitine

For those that feel only trimethylamine causes their odor, perhaps carnitine is worth further investigation to see if this could be a secret source of TMA in your diet. In general, it seems that those on a strict vegetarian or vegan diet may have very little carnitine in their diet, but it must be remembered that lysine and methionine are essential amino acids.


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