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anti-TMA pill in a year or 2 ? (scroll 12 mins)

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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

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Denver TMAU Test Lab survey click here
click to Read more/less

USA survey for anyone who wants to improve Denver TMAU test

begun : Dec22
end : no ending for now

A trainee genetic counselor is working at the Denver TMAU test lab. Probably as part of her training. As a project she wishes feedback on any aspect of the Denver TMAU test and process. You can fill in the survey and/or email her (email address is in survey). It's meant for USA people, but perhaps others can give their view too (as we have so few opportunities).

quote from her rareconnect post

"Hello all! I wanted to make you aware of a research study being conducted to better understand the experience and needs of individuals with trimethylaminuria with a goal of being able to create improved patient and healthcare provider education materials. Any participation is completely voluntary and all responses remain confidential. Feel free to use the contact information within the link with any questions or share the survey with others with TMAU."

see this post for more details

Wednesday, March 14, 2012

MEBO gut dysbiosis in body odor and halitosis cases : Tester 14 results

MEBO gut dysbiosis study
Tester 14 results

Below are the results of tester 14 in our gut dysboisis study. A young lady with a fecal body odor problem for about 2 years. She thinks it is an 'anal odor' problem.

Tester 14
Female, early 20's
Odor problem:
Fecal body odor for 2 years. Mostly can't smell it. Others tell her. 
Gut problems
IBS symptoms. Crave simple carbs. Feel wrose on probiotics but hoping it's a good thing.
Other problems
Tired, post nasal drip,  tonsilloliths , thrush, acne 
Not tested

Results :
Tester 14 (click on photos)
Gut Fermentation
Ethanol raised
Also 2-methyl-1-propanol

Gut permeability
Normal profile


D Lactate



body odor gut dysbiosis study
Our study overseer, Professor Irene Gabashvilli, had these comments to make on the results

Your results are most similar to our Tester #3 who also had high ethanol, and high or borderline 1-propanol, 2-methyl-1-propanol, and 2-methyl-1-butanol. This tester's short chain fatty acid profile was also normal, while indicans was positive. This person was complaining of "slightly unusual "anal" odor" too.

High ethanol might not necessarily mean yeast overgrowth, bacteria can produce ethanol too. Positive indicans is a sign of abnormal bacterial colonization in the small intestine, and could imply many different things including pancreatic insufficiency or celiac disease. By the way, tester #3 was suspecting sensitivity to gluten.

Below are some comments from tester 14 herself about her condition

Other people comment on a fecal smell (I am not able to smell it myself, only very occasionally). It just leaks out without any control over it.

symptoms : Bloating, Constipation, Gas, Pale coloured stools, Stomach or lower abdominal pain, Undigested food in stool when consumed too much fructose

Fructose malabsorption- found through diet (exempting food high in fructose) that I do not suffer from diarrhea anymore, but this does nothing to prevent the fecal odour.

crave simple carbs

probiotics Feel worse but suspect it is a good reaction

other symptoms : Tired, post nasal drip, tonsilliths, thrush, acne

Any connections : Stress makes it much much worse, especially social situations. Consuming foods high in fructose makes the amount of gas I suffer from worse, increases bloating. Period causes constipation which I find makes it much worse.

Comment on the study : It is finally nice to see actual research taking this serious. All the doctors I have been to think I am exaggerating, or do not listen to me properly or just think I am anxious.

The summary of all results can be seen in this table
MEBO gut dysbiosis study in self-reported cases of body odor or halitosis

body odor petition
MEBO Research


dee1 said...

the comments i have seen here are similar to what i experience and it has been traumatising for me. i have tried many perfumes, anti perspirants and deodorants but none seems to work. the distressing part is that i use public transport and reactions and comments from people on buses and coaches have made me clusterphobic and loose my confidence.

please how can i join a meet up. i live in leeds

Mar 17, 2012, 9:50:00 AM
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