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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

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at UK Findacure conf 2020

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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect

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Blog Archive

MEBO Research Clinical Trials

Click here to read details of the MEBO Clinical Trials
NCT03582826 - Ongoing not recruiting
Microbial Basis of Systemic Malodor and PATM Conditions (PATM)
United States 2018 - ongoing

NCT02683876 - Completed
Exploratory Study of Relationships Between Malodor and Urine Metabolomics
Canada and United States 2016 - ongoing

NCT03451994 - Completed
Exploratory Study of Volatile Organic Compounds in Alveolar Breath
United Kingdom and United States 2013 - ongoing

NCT02692495 - Completed
Evaluation of Potential Screening Tools for Metabolic Body Odor and Halitosis
United Kingdom 2009 - 2012

Sunday, September 2, 2012

TMAU result stats from Sheffield UK 1997-2011

As part of conference at the recent MEBO Research Miami Beach Meetup in June, Nigel Manning, Principal Clinical Scientist in the department of Metabolic Biochemistry at Sheffield Children's Hospital (i.e. the UK TMAU tester), kindly provided MEBO with the latest statistics on their urine (phenotype) triemthylaminuria testing program.

A bar graph and dot graph were kindly provided. A trend of note was the bar graph shows that TMAU testing requests increased significantly since 2006, and especially over the last 2 years (to nearly 600 requests per year).

Note : Each TMAu lab sets their own reference range. The Sheffield ref ranges using gas chromatography are :
TMA concentration normal : 2.5-10.9 umol/mmol creatinine
TMAO normal : 17-147 umol/mmol creatinine
TMA/TMAO ratio normal : 0.05-0.21 (% TMAO should be, according to diagram, >79%)

bar graph of Sheffield TMAU results 97-11
dot graph of Sheffield TMAU results 97-11

PDF : Sheffield UK TMAU results 1997-2011 as a bar graph
PDF : Sheffield UK TMAU results in a dot graph with reference range lines

MEBO Research


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