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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect

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MEBO Research Clinical Trials

Click here to read details of the MEBO Clinical Trials
NCT03582826 - Ongoing not recruiting
Microbial Basis of Systemic Malodor and PATM Conditions (PATM)
United States 2018 - ongoing

NCT02683876 - Completed
Exploratory Study of Relationships Between Malodor and Urine Metabolomics
Canada and United States 2016 - ongoing

NCT03451994 - Completed
Exploratory Study of Volatile Organic Compounds in Alveolar Breath
United Kingdom and United States 2013 - ongoing

NCT02692495 - Completed
Evaluation of Potential Screening Tools for Metabolic Body Odor and Halitosis
United Kingdom 2009 - 2012

Wednesday, June 4, 2014

MEBO TMAU Test Program Results: BATCH #10

Click on icon to see chart

The MEBO Research TMAU urine test program was launched 2 years ago this month, on June 2012, and MEBO has received 208 test results during this time, including the results of the first batch from the DLE - Medicina Laboratorial in Brazil. Some of these 208 results have been very interesting and helpful to many sufferers from around the world. For example, some women have done two tests collecting samples two weeks apart, and some have received results that indicate transient trimethylaminuria, possibly associated with menstruation. Others have received positive results that they have taken to their physician with the TMAU literature that is attached to the results, and have received a great deal of support from their physician, most of whom had never heard of TMAU before.

Other sufferers have received negative results indicating that TMAU is not the cause of their problem. This can serve to ease their minds knowing that they do not need to go on a low choline diet. Nonetheless, because this test has told them what they don't have as opposed to what they do have, it leaves the sufferer without direction because there are no other odor-type tests other than the ones normally prescribed by physicians for medical conditions that produce odor, such as diabetes, kidney failure, liver failure, cancer, gingivitis, tonsillitis, etc. So what do sufferers do to try to control their odor when they've received a negative result? The following list has helped some sufferers reduce, if not completely control their odor symptoms.


  1. Observe one's bowel function. Is there a tendency for constipation, diarrhea, or alternate from one to the other, or are bowel movements voluminous and regular? The place where most of the odorous chemicals (not only TMA, but other chemicals as well) are formed is in the gut (colon) by the microflora, and these odorous chemicals pass into the blood stream. There are some microbes in the gut that produce more odorous compounds than others. When one is experiencing high odor levels, periodic cleansing of the gut is recommended on a day that one can stay home, to thoroughly clean out one's intestines.
  2. If possible and under a doctor's care, do a course of antibiotics immediately followed by a course of probiotics. Even if an antibiotic treatment is not done, a laxative cleans followed by probiotics is beneficial.
  3. Avoid spicy foods or foods that have a strong odor. Whenever odorous foods are consumed, the odorous chemicals are entering the body.
  4. Avoid sulfur foods, like onions, garlic, etc. See list of Sulphur Contents of Foods
  5. Eat natural foods, especially fruits and vegetables, double fiber cereals, English muffins, and/or Arnold Double Fiber bread. If one doesn't eat much fiber on a regular basis, one might want to begin introducing it slowly and increasing the amount of natural fiber in foods as tolerated. If a sudden large amount of fiber is suddenly consumed, it might produce flatulence and discomfort.
  6. Restrict red meat consumption to small portions, and icrease chicken and some fish or seafood in diet.
  7. Exercise...this helps clean out one's system with perspiration and deep fast breathing. As one continue doing this, the saturation level of the odorous chemicals will slowly but surely decrease.
  8. Drink A LOT of water throughout the day to help flush any odorous chemicals.
  9. Since the test result was negative TMAU, there might not be a need to use acidic soaps, and more pH balanced body washes and shampoos might be more effective.
  10. If halitosis is a concern, consult with a dentist for a thorough oral checkup.
  11. If on has sinus problems or tonsil problems, a consultation with an otolaryngologist (ears, nose, and throat specialist) is recommended.
  12. If one has underarm and/or groin odor, discuss with physician and or a dermatologist to see if they want to prescribe topical medication.

Important questions to ask oneself:
  1. Do I suffer from halitosis? (Scroll down to see all posts)
  2. Foot odor?
  3. Bromhidrosis (uncontrollable underarm odor?
  4. Scalp odor?
  5. Odor around neck, chest, and back?


María de la Torre
Founder and Executive Director

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