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MEBO TMAU TESTING CURRENTLY SUSPENDED INDEFINITELY

MEBO - UBIOME study 2018

'PRESS RELEASE'

NCT03582826
ClinicalTrials.gov

MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production
& PATM

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person

NO LONGER RECRUITING

Participation info : LINK English

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Metabolomic Profiling Study
NCT02683876

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
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MEBO Research Clinical Trials

Click here to read details of the MEBO Clinical Trials
NCT03582826 - Ongoing not recruiting
Microbial Basis of Systemic Malodor and PATM Conditions (PATM)
United States 2018 - ongoing

NCT02683876 - Completed
Exploratory Study of Relationships Between Malodor and Urine Metabolomics
Canada and United States 2016 - ongoing

NCT03451994 - Completed
Exploratory Study of Volatile Organic Compounds in Alveolar Breath
United Kingdom and United States 2013 - ongoing

NCT02692495 - Completed
Evaluation of Potential Screening Tools for Metabolic Body Odor and Halitosis
United Kingdom 2009 - 2012

Tuesday, August 20, 2019

Epulopiscium bacteria in odor conditions

https://aurametrix.com/blog/balance.html

NCT03582826 - Ongoing not recruiting
Microbial Basis of Systemic Malodor and PATM Conditions (PATM) 
United States 2018 - ongoing

...this is not the only responsible microorganism for odors or PATM. We will be reporting more, along with what seem to help in reducing the levels.
Although Irene is still waiting for the final results of the 4th batch of participants from uBiome, she has been analyzing all the gut microbiome results she has received so far. A significant finding that applies only to some of the participants with odor conditions is a group of Gram-positive bacteria found at high levels on sufferers who have very strong odor. This unusually large size, or “giant” bacteria has the genus name of Epulopiscium, and is more commonly found in the gut of brown surgeonfish.

Irene Gabashvili, PhD., MEBO Scientific Director and Principle Investigator of the study, wrote a post in her Aurametrix Blog, "The Delicate Balance, NCT03582826" about this finding in which she states:


Epulopiscium was found in only 5% of general population that tested with uBiome. But we see a much higher percentage of these bacteria in our samples, depending on the symptoms reported.

It could be as high as 50% in the sufferers experiencing the worst symptoms, decreasing as symptoms lessen...

Of course, this is not the only responsible microorganism for odors or PATM. We will be reporting more, along with what seem to help in reducing the levels.

We will also tell about bacteria "neutralizing" the odors, found in remission. Some of them are antiinflammatory, others help with digestion.
https://aurametrix.com/blog/balance.html

Irene Gabashvili, PhD., is our MEBO Scientific Director and Principal Investigator of the MEBO Gut Microbiome Study sponsored by a uBiome Grant.

For additional reading on the Epulopiscium fishelsoni, see article in the New York Times, March 18, 1993, Section D, Page 22, original in the British journal, Nature.


Pulverizing the genetic material from the bacteria, the researchers then multiplied the DNA into millions of copies through the use of a technique called polymerase chain reaction. They next compared the genes with those from many other known prokaryotes and eukaryotes and demonstrated that E. fishelsoni is a true bacterium, a member of the microbial family that includes the botulism pathogen.
https://www.nytimes.com/1993/03/18/us/in-the-world-of-bacteria-a-behemoth.html

To see all posts in this blog on the MEBO Gut Microbiome Study, scroll down and click on 'Older Posts' on this link, http://www.meboblog.com/search/label/MEBO%20Gut%20Microbiome%20Study

María


María de la Torre
Founder and Executive Director

A Public Charity
maria.delatorre@meboresearch.com
www.meboresearch.org
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