The Hazen Cleveland lab team put forward the TMAO-Hypothesis in 2011, and have been looking at ways to inhibit trimethylamine formation in the gut (as well as other things).
In this March podcast, Dr Hazen says (quote ... roughly) :
1. DMB inhibited TMA formation in gut by about 98% (they are using other stronger inhibitors now it seems).
2. Human trials will begin in 2020.
Dr Hazen also says (something like)
"now whether it will be commercially available this year, I don't know".
From that you could wonder that the Procter & Gamble anti-TMA pill might be available to buy in the near future ... say a year or 2 or 3 ?
It will be available to buy over-the-counter.
5 comments:
Would it be possible to have another company make a pill combining pure resveratrol with DMB and market that on a small scale to TMAU sufferers?
Keep in mind that the human trial phase is for cardiovascular disease, not for TMAU patients. Repurposing this product for TMAU has not been researched yet.
Anonymous, any company can sell DMB once it has satisfied the FDA research requirements.
Regarding Dr. Hazen's product, I don't know if it only has DMB or what other ingredients it may have. I believe it has been patented, so no other company can reproduce it exactly the same, and no other company that I know of would have researched it as thoroughly as Dr. Hazen's lab has these past few years.
Sell all posts in this blog on DMB:
https://www.meboblog.com/search/label/DMB
Are there any update on this?