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March20 podcast Dr Hazen
anti-TMA pill in a year or 2 ? (scroll 12 mins)

Additional info:
MEBO Karen
at UK Findacure conf 2020

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MEBO Map Testing & Meetups

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MEBO - UBIOME study 2018



MEBO Gut Microbiome Study
"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"
Funded by uBiome Research Grant

"Microbial Basis of Systemic Malodor and PATM Conditions (PATM)"

Dynamics of the Gut Microbiota in
Idiopathic Malodor Production

Started May 2018 - Ongoing

Current people sent kits : 100/100
3 kits per person


Participation info : LINK English

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BO Sufferers Podcasts



TMAU Petition world
TMAU UK end total:262
TMAU UK ends 23/01/20
TMAU Petition USA end total 204
USA : Moveon open
TMAU (Dominican)
Metabolomic Profiling Study

Start : Aug 2016
Stage 1 : 27 Canadian volunteers to test
Latest click here (26 oct) :
17 samples returned

Note : Stage 1 is Canada only.
Return cut-off date : passed
Analysis can take 6/8 weeks
Analysis start in/before Nov
MEBO Research is a
NORD Member Organization
See RareConnect TMAU

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MEBO Metabolic Malodor Survey (international) for Dr Hazen click here
click to Read more/less

survey for ANYONE who identifies with METABOLIC MALODOR

begun : Oct20
end : no ending for now

Regular readers will know that Dr Stan Hazen et al at Cleveland Clinic are developing a TMA-blocker pill, as they proposed in a 2011 paper that TMAO is a factor in CVD. Recently Dr Hazen and colleagues contacted MEBO as they have always thought they could also help with TMAU. This survey is to give them an idea of the 'state of the community'. It is a "version 1". They may not even look (though they have access permission), but it could be useful to give them an overview of the community

MEBO had a zoom call with Dr Hazen and his team in October. Another zoom call is planned when they have time

This is a GOOGLE FORMS survey

short url for survey :

current participants : 113 (update 18dec20)

Friday, June 5, 2020

Odor-Management is twofold


In most conditions, the odor management process has to be two-fold:

1.    Firstly, by stopping the introduction of odorous compounds into the body through diet.  Poorly metabolized odorous compounds at higher than normal levels will remain flowing in the bloodstream and are stored in body fat.
2.    Secondly, by assisting the body’s cleansing organs in eliminating odorous compounds.

This paper does not discuss which diet is appropriate for different causes of difficult to control body odor and/or halitosis.  The focus is on assisting and boosting the natural processes of the body’s cleansing organs.

When not addressing both aspects of odor-management, many sufferers misinterpret the results of their odor-management efforts as they attempt to self-diagnose and to explore management measures. They might have been on the perfect diet for their personal specific condition, but since the compounds are already stored in body fat and are still flowing in the bloodstream, their body and/or breath odor will continue to exist until they are cleaned out of the body. This confuses the sufferer into believing that he or she has not been able to target and manage the specific cause of odor, when in fact, only one of the two processes was actually addressed. Mistakenly, the sufferer incorrectly determines that the diet did not help, when it fact, diet alone might have addressed only one of the two required processes. 


The capillaries in the alveoli in the lungs are where the exchange of compounds take place to/from the blood and the breath. This is why the lungs act as a cleansing organ. Gasses like carbon dioxide and many odorous compounds leave the blood by passing into the lung alveoli to be released in the exhaled breath, while oxygen enters the body through inhaled breath and enters the bloodstream through the capillaries in the alveoli. During this process, odorous breath is expelled from the blood very much faster when the heart rate and respiratory rate increases with cardiovascular exercise.  One can rest assured that this gas exchange is taking place when feeling the heart beating much faster and the breathing rate increasing automatically with exercise.  Eventually, the amount of odorous compounds in the blood decrease minimizing halitosis, as long as it is not introduced back into the body with improper diet. Without cardiovascular exercise, this faster process decreases and it takes longer to control systemic body odor and/or halitosis.

This explains why stress increases the odor symptoms. When under stress, the heart rate and breath rate increases and thus more compounds from the blood come out in the breath, skin oils and perspiration. The sufferer is in greater control when increasing the heart and breath rate while exercising in a controlled environment, as opposed to waiting for a stressful social situation in which the heart and breath rate increases producing body and/or breath odor.


In addition to cardiovascular exercise, detox diets, which usually require increased hydration, help eliminate odorous chemicals from the body.  On the other hand, starvation diets may actually increase odor due to ketones.

It is also important to keep in mind that our body’s immune system fights infection through our mucous membranes and moisture on our skin, excessive cleaning of the sinuses and mouth may end up increasing halitosis symptoms by weakening our antibody filled mucous/saliva. This is why people with dry mouth syndromes, like Sjogren's Syndrome, can develop halitosis due to there not being enough natural moisture in the oral cavity resulting in increased microbial growth.


María de la Torre
Founder and Executive Director

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