DMB and Resveratrol both inhibit choline from being converted to odorous TMA by gut bacteria in a slightly different way. Resveratrol encourages good bacteria to flourish (Lactobacillus and Bifido). Resveratrol increased levels of the genera Lactobacillus and Bifidobacterium, which increased the bile salt hydrolase activity, thereby enhancing bile acid (BA) deconjugation and fecal excretion,
… Resveratrol inhibits TMA production by gut bacteria... In our current study, we found that resveratrol can remodel the gut microbiota including increasing the Bacteroidetes-to-Firmicutes ratios, significantly inhibiting the growth of Prevotella, and increasing the relative abundance of Bacteroides, Lactobacillus, Bifidobacterium, and Akkermansia in mice," said Dr. Mi. "Resveratrol reduces TMAO levels by inhibiting the gut microbial TMA formation via remodeling gut microbiota. https://www.sciencedaily.com/releases/2016/04/160405105547
htm http://www.eurekalert.org/pub_releases/2016-04/asfm-ttg033116.php
One could still debate that Resveratrol acting like a prebiotic or probiotic in shifting gut flora may be bad for you- but then one would also have to argue that any fermented food or probiotic is also harmful -- or even meat is harmful because it also shifts gut flora. At least there is a study with Resveratrol which proposes which gut flora species it shifts to, unlike most/many other gut flora changers. But for TMAU, the proposed theory behind Resveratrol is what we have been looking for, second to an FMO3 booster, which is going to take years to get through the Trinzyme research study, which is ready for clinical trials stage pending funding.
Please keep in mind that especially if you have tested negative for TMAU, what works for TMAU sufferers may not work for you at all if you don't have TMAU. Note that there has been no serious research on resveratrol's effects on body odor or even on general health with long-term use. If you think resveratrol may be causing you side effects, it is be best for you to discontinue using it and consult with your doctor.
CAUTION: Some sufferers have found that Resveratrol increases their blood pressure. Please check your blood pressure before and during taking resveratrol.
"Caution: Persons taking medications that affect platelet aggregation (such as aspirin, warfarin, NSAIDs) or persons with bleeding disorders, such as peptic ulcers should consult a healthcare professional before using grape seed extract."
Nature's Way Premium Extract Grape Seed vcaps
"Caution: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this [resveratrol] or any dietary supplement."
BRI Resveratrol Extra Strength
Possible "Side effects may include minor gastrointestinal upset, nausea, headache and fatigue and possible supplement-drug interactions with estrogens and anticoagulants."
Please always take heed and beware when a sufferer tells you that a product or diet has not been research for body or breath odor conditions, or whether it has been researched ONLY for TMAU, which you might not have. It might not, and probably will not, work for you. As far as I know, no halitosis or body odor expert has recommended resveratrol for these conditions, and therefore, MEBO does not recommend it either. It is an interesting product worthy of further research in relation to halitosis and body odor.
María

Founder and Executive Director

A Public Charity
maria.delatorre@meboresearch.com
www.meboresearch.org
www.mebo.com.br/
MEBO's Blog (English)
El Blog de MEBO (español)
MEBO Brasil - Blog (Portuguese)

0 comments: